Now showing items 11-20 of 23
A NMR Investigation of Structure and Allostery in the Hsp70 Chaperone System.
(2010)
The Hsp70 Chaperone system is a complex molecular machine composed of proteins. It is responsible for assisting in protein folding/refolding/processing and transport. Hsp70 proteins have been historically associated with ...
Molecular characterization of the endoplasmic reticulum: Insights from proteomic studies
(WILEY-VCH Verlag, 2010-11)
The endoplasmic reticulum (ER) is a multifunctional intracellular organelle responsible for the synthesis, processing and trafficking of a wide variety of proteins essential for cell growth and survival. Therefore, ...
Compartmentalization of Gold Nanocrystals in Polymer Microparticles using Electrohydrodynamic Co-Jetting
(WILEY-VCH Verlag, 2010-01-18)
Polymer particles with micro- and nanoscale anisotropy have received increasing interest for their ability to simultaneously present different physical- and chemical properties. In this communication, we demonstrate that ...
Glycoprotein analysis using protein microarrays and mass spectrometry
(Wiley Subscription Services, Inc., A Wiley Company, 2010-09)
Protein glycosylation plays an important role in a multitude of biological processes such as cell–cell recognition, growth, differentiation, and cell death. It has been shown that specific glycosylation changes are key in ...
Predictors of alternative antidepressant agent initiation among U. S. veterans diagnosed with depression
(John Wiley & Sons, Ltd., 2010-10)
OBJECTIVES Naturalistic studies comparing differences in risks across antidepressant agents must take into account factors which influence selection of specific agents and may be associated with outcomes. We examined ...
Toward Assembly of Non-close-packed Colloidal Structures from Anisotropic Pentamer Particles
(WILEY-VCH Verlag, 2010-01-18)
Particles combining multiple anisotropy dimensions offer possibilities for self-assembly that have not been extensively explored to date. The scope for assembly of microparticles in which the anisotropy dimensions of ...
Thiazolidinediones, cardiovascular disease and cardiovascular mortality: translating research into action for diabetes (TRIAD)
(John Wiley & Sons, Ltd., 2010-07)
Background Studies have associated thiazolidinedione (TZD) treatment with cardiovascular disease (CVD) and questioned whether the two available TZDs, rosiglitazone and pioglitazone, have different CVD risks. We compared ...
Fluoride catalyzed rearrangements of polysilsesquioxanes, mixed Me, vinyl T 8 , Me, vinyl T 10 and T 12 cages
(John Wiley & Sons, Ltd., 2010-08)
Insoluble mixtures of polyvinylsilsesquioxane, -(vinylSiO 1.5 ) n - PVS, and polymethylsilsesquioxanes, -(MeSiO 1.5 ) n - PMS, in THF at ambient when treated with catalytic amounts (1–5 mol%) of fluoride ion introduced ...
Rate constant of the reaction of chlorine atoms with methanol over the temperature range 291–475 K
(Wiley Subscription Services, Inc., A Wiley Company, 2010-02)
The rate constant of the reaction Cl + CH 3 OH ( k 1 ) has been measured in 500–950 Torr of N 2 over the temperature range 291–475 K. The rate constant determination was carried out using the relative rate technique with ...
Targeting the BCL9/B9L Binding Interaction with B-catenin as a Potential Anticancer Strategy.
(2010)
Wnt signaling plays a critical role in numerous cellular processes including embryonic development, cell proliferation and tissue homeostasis. The multifunctional protein β-catenin is the primary mediator of canonical Wnt ...