Now showing items 411-420 of 466
A convenient synthesis of -(5'-deoxy-5'-adenosyl)- (+/-) -2-methylhomocysteine
(Elsevier, 1985)
The synthesis of -(5'-deoxy-5'-adenosyl)-+-2-methylhomocysteine in two steps from +--2-methylmethionine is described.
Reverse-phase high-performance liquid chromatography of hydrophobic proteins and fragments thereof
(Elsevier, 1983-05)
Reverse-phase high-performance liquid chromatography (HPLC) resolution and recovery of cytochrome P-450 and bovine rhodopsin, both integral membrane proteins, and large peptides derived from P-450 LM2 were enhanced by ...
Rapid reductive-carboxylation of secondary amines. One pot synthesis of tertiary N-methylated amines
(Elsevier, 1985)
Various tertiary N-methylated amines were synthesized by using a new reductive-carboxylation approach. Secondary amines, on carboxylation with carbon dioxide under moderate reaction conditions, afforded their corresponding ...
The cytokinetic and cytotoxic effects of ICRF-159 and ICRF-187 in vitro and ICRF-187 in human bone marrow in vivo
(Kluwer Academic Publishers; Martinus Nijhoff Publishers ; Springer Science+Business Media, 1983-12)
The cytotoxic and cytokinetic effects of ICRF-159 and its d-enantiomer ICRF-187 have been examined in vitro . The effects of both agents were identical. Cytotoxicity is dependent on both the drug concentration and the ...
Characterization and quantitation of 3-alkylthymidines from reactions of mutagenic propylene oxides with thymidine
(Elsevier, 1984-12)
Thymidine was reacted in methanol with four epoxides of varying mutagenicities: propylene oxide, glycidol, epichlorohydrin and trichloropropylene oxide. A single product was detected with each epoxide, and these products ...
Carbon monoxide oxidation under transient conditions: A fourier-transform infrared transmission spectroscopy study
(Elsevier, 1985-07)
In contrast to the apparent simplicity of the overall reaction, oxidation of CO over Pt/A2O3 is known to present complex behavior. Self-sustained oscillations, hysteresis loops in conversion, and enormous rate enhancements ...
Use of monoclonal antibody probes against rat hepatic cytochromes P-450c and P-450d to detect immunochemically related isozymes in liver microsomes from different species
(Elsevier, 1984-11-15)
Nine distinct monoclonal antibodies raised against purified rat liver cytochrome P-450c react with six different epitopes on the antigen, and one of these epitopes is shared by cytochrome P-450d. None of these monoclonal ...
Glycosyltransferase activities of Ehrlich ascites tumor cells: Detection, isolation, and characterization using oligosaccharide-Synsorb beads
(Elsevier, 1987-04)
Detergent extracts of Ehrlich tumor cell membranes exhibit a host of glycosyltransferase activities which have been investigated using oligosaccharides immobilized to Synsorb beads as acceptors. Glycosidase digestions in ...
Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. IV. Degradation by heat and proteolysis of normal and variant carbonic anhydrase isozymes of Macaca nemestrina
(Elsevier, 1984-04)
Studies were undertaken on the heat denaturation and proteolytic degradation by [alpha]-chymotrypsin of the normal red cell carbonic anhydrase isozyme, CA II, and two electrophoretic variants of carbonic anhydrase I, CA ...
Reduction of ketones by sodium borohydride in the absence of protic solvents. Inter versus intramolecular mechanism
(Elsevier, 1982)
Acetone, acetophenone and benzophenone react with sodium borohydride in the absence of protic solvent to give the corresponding tetraalkoxyborates. In view of theseresults, the possibility of the 4-centre mechanism for ...