Now showing items 121-130 of 897
Multi‐SKAT: General framework to test for rare‐variant association with multiple phenotypes
(Wiley Periodicals, Inc., 2019-02)
In genetic association analysis, a joint test of multiple distinct phenotypes can increase power to identify sets of trait‐associated variants within genes or regions of interest. Existing multiphenotype tests for rare ...
T h1‐mediated experimental autoimmune encephalomyelitis is CXCR 3 independent
(Wiley Periodicals, Inc., 2013-11)
Proteomic analysis of cold adaptation in a Siberian permafrost bacterium – Exiguobacterium sibiricum 255–15 by two-dimensional liquid separation coupled with mass spectrometry
(WILEY-VCH Verlag, 2006-10)
Bacterial cold adaptation in Exiguobacterium sibiricum 255–15 was studied on a proteomic scale using a 2-D liquid phase separation coupled with MS technology. Whole-cell lysates of E. sibiricum 255–15 grown at 4°C and ...
Bio‐Orthogonal Polymer Coatings for Co‐Presentation of Biomolecules
(WILEY‐VCH Verlag, 2012-04-23)
Controlled presentation of biomolecules on synthetic substrates is an important aspect for biomaterials development. If the immobilization of multiple biomolecules is required, highly efficient orthogonal surface chemistries ...
Building on the past, shaping the future: The environmental mutagenesis and genomics society
(Wiley Periodicals, Inc.Plenum Press, 2013-04)
Glycine Protection of PC-12 Cells Against Injury by ATP-Depletion
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2003-06)
A distinctive mechanism of cell injury during ATP depletion involves the loss of cellular glycine. The current study examined whether provision of glycine during ATP depletion can prevent injury in PC-12 cells, a cell line ...
Cell line dependent involvement of ceramide in ultraviolet light-induced apoptosis
(Kluwer Academic Publishers; Springer Science+Business Media, 2001-03)
Ultraviolet light (UV) activates an acid sphingomyelinase (ASMase) pathway, which hydrolyzes sphingomyeline to ceramide. Ceramide has been found to be a second messenger, which activates the c-jun N-terminal kinase (JNK) ...
SRM targeted proteomics in search for biomarkers of HCV ‐induced progression of fibrosis to cirrhosis in HALT ‐ C patients
(Wiley Periodicals, Inc.Springer, 2012-04)
Characterization of a highly flexible self‐assembling protein system designed to form nanocages
(Oxford University PressWiley Periodicals, Inc., 2014-02)
The design of proteins that self‐assemble into well‐defined, higher order structures is an important goal that has potential applications in synthetic biology, materials science, and medicine. We previously designed a ...