Now showing items 1961-1970 of 1994
Oxidation of 2-keto-4-hydroxyglutarate by pig heart and Escherichia coli [alpha]-ketoglutarate dehydrogenase complex
(Elsevier, 1979-01)
Enzyme preparations from pig heart and Escherichia coli have been found to catalyze a NAD+- and CoASH-dependent oxidation of 2-keto-4-hydroxyglutarate. Several independent lines of evidence indicate that 2-keto-4-hydroxyglutarate ...
Stereoselective β‐Mannosylation via Anomeric O‐Alkylation with L‐Sugar‐Derived Electrophiles
(Wiley Periodicals, Inc., 2021-12-28)
A total synthesis of the trisaccharide repeat unit of Salmonella serogroup E1 O‐antigen is reported. This synthesis features a key β‐mannosylation reaction through a cesium carbonate‐mediated anomeric O‐alkylation of a ...
Use of a mobile app to capture supplemental health information during pregnancy: Implications for clinical research
(John Wiley & Sons, Inc., 2022-01)
PurposeMobile applications (- apps- ) may be efficient tools for improving the quality of clinical research among pregnant women, but evidence is sparse. We assess the feasibility and generalizability of a mobile app for ...
Facile Fabrication of Anisotropic Multicompartmental Microfibers Using Charge Reversal Electrohydrodynamic Co‐Jetting
(Wiley Periodicals, Inc., 2022-01)
Anisotropic microstructures are utilized in various fields owing to their unique properties, such as reversible shape transitions or on‐demand and sequential release of drug combinations. In this study, anisotropic ...
Curcumin downregulates the PI3K–AKT–mTOR pathway and inhibits growth and progression in head and neck cancer cells
(John Wiley & Sons, Ltd., 2020-12)
Curcumin, a polyphenol isolated from the rhizome of Curcuma longa, has been studied because of its antioxidant, antimicrobial, and antiinflammatory properties. This study aimed to evaluate the effects of curcumin on head ...
Multifunctional Synthetic Protein Nanoparticles via Reactive Electrojetting
(Wiley Periodicals, Inc., 2020-12)
Protein nanoparticles are a promising approach for nanotherapeutics, as proteins combine versatile chemical and biological function with controlled biodegradability. In this work, the development of an adaptable synthesis ...
ProTrack: An Interactive Multi‐Omics Data Browser for Proteogenomic Studies
(Wiley Periodicals, Inc., 2020-11)
The Clinical Proteomic Tumor Analysis Consortium (CPTAC) initiative has generated extensive multi‐omics data resources of deep proteogenomic profiles for multiple cancer types. To enable the broader community of biological ...
Comparison of Proteomic Assessment Methods in Multiple Cohort Studies
(Humana PressWiley Periodicals, Inc., 2020-06)
Effects of stereoisomeric structure and bond location on the ignition and reaction pathways of hexenes
(Wiley Periodicals, Inc., 2021-02)
The current work presents new experimental autoignition and speciation data on the two cis- hexene isomers: cis- 2- hexene and cis- 3- hexene. The new data provide insights on the effects of carbon- carbon double ...