Now showing items 51-60 of 102
[kappa]1 Receptor mRNA Distribution in the Rat CNS: Comparison to [kappa] Receptor Binding and Prodynorphin mRNA
(Elsevier, 1994-04)
Three opioid receptor types have been identified in the CNS and periphery that are referred to as [mu], [delta], and [kappa]. The present study examines the mRNA distribution of the [kappa]1 receptor in the rat brain and ...
Glutamate uptake system in the presynaptic vesicle: Glutamic acid analogs as inhibitors and alternate substrates
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1993-01)
A variety of naturally occurring amino acids, their isomers, and synthetic analogs were tested for their ability to inhibit uptake of [ 3 H]glutamate into presynaptic vesicles from bovine cerebral cortex. Strongest inhibition ...
Autoradiographic quantification of muscarinic cholinergic synaptic markers in bat, shrew, and rat brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
We employed radioligand binding autoradiography to determine the distributions of pre- and postsynaptic cholinergic radioligand binding sites in the brains of two species of bat, one species of shrew, and the rat. High ...
The psychobiology of premenstrual dysphoria: The role of prolactin
(Elsevier, 1978)
(1) The evidence for a role of prolactin in the premenstrual syndrome is discussed in this review. (2) The timing of the onset and offset of both physical and psychological dysphoric symptoms corresponds with the luteal ...
Molecular and electrophysiological characterization of a allelic variant of the rat [alpha]6 GABAA receptor subunit
(Elsevier, 1992-11)
A 1.45 kb DNA sequence encoding the rat [alpha]6 GABAA receptor subunit (nucleotides 33-1483) was clonedfrom a Sprague-Dawley rat brain cDNA library by PCR amplification. Dideoxy sequencing of two individual clones revealed ...
Tyrosine hydroxylase mRNA-containing neurons in the medial amygdaloid nucleus and the reticular nucleus of the thalamus in the Syrian hamster
(Elsevier, 1993-11)
To confirm previous immunocytochemical findings in colchicine-treated Syrian hamsters, in situ hybridization was used to investigate the distribution of TH mRNA-containing cells in the medial amygdaloid nucleus (Me) and ...
William Hogarth, Unwitting Neurochemist?
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2000-10)
William Hogarth's famous etching Gin Lane is often used to illustrate the debilitating results of alcohol addiction. Less well known is the companion etching Beer Street in which death, murder and squalor are replaced by ...
The developmental pattern of homologous and heterologous tRNA methylation in rat brain differential effect of spermidine
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1976-08)
Using S -adenosyl- L -[Me- 14 C] methionine, rat cerebral cortex methyltransferase activity was determined during the early postnatal period in the absence of added Escherichia coli tRNA and in its presence. [Me- 14 C] ...
Effects of fluoxetine on weight gain and food intake in smokers who reduce nicotine intake
(Elsevier, 1991)
The effect of fluoxetine hydrochloride, a 5-HT uptake inhibitor (60 mg/day PO), in preventing weight gain associated with nicotine reduction was investigated in participants in a double-blind, placebo-controlled smoking-cessation ...
Cloning and expression of the A 2a adenosine receptor from guinea pig brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
A full-length complementary DNA (cDNA) clone encoding the guinea pig brain A 2 adenosine receptor has been isolated by polymerase chain reaction (PCR) and low-stringency-hybridization screening of a guinea pig brain cDNA ...