Now showing items 71-80 of 810
Strategies for studying opioid peptide regulation at the gene, message and protein levels
(Elsevier, 1984)
Three opioid peptide precursors have been isolated and characterized in endocrine and nervous tissue: pro-opiomelanocortin, pro-enkephalin, and pro-dynorphin. Since each of those opioid peptide systems have been extensively ...
Sensitive high-performance liquid chromatographic assay using 9-fluorenylmethylchloroformate for monitoring controlled-release lidocaine in plasma
(Elsevier, 1989)
A sensitive high-performance liquid chromatographic (HPLC) assay using fluorescence detection for quantifying lidocaine levels in plasma (in the ng/ml range) was developed. This novel HPLC assay has made possible the ...
Biological effects of a novel intestinal peptide -- inhibiting enterocytogenin on cultured 3T3 mouse fibroblasts and L5178Y mouse lymphoma cells
(Elsevier, 1994-05-05)
The effects of a new intestinal peptide, inhibiting enterocytogenin (IEG) derived from pig intestinal mucosa were studied in vitro on 3T3 mouse fibroblasts and L5178Y mouse lymphoma cell line. IEG caused considerable growth ...
Chemoenzymatic Preparation of Nucleoside Triphosphates
(Wiley Periodicals, Inc., 2004-03)
The design and synthesis of alternative nucleoside triphosphate substrates for DNA and RNA polymerases holds continued promise to create biochemical probes and precursors for synthesis of nucleic acid mimics. The azole ...
The heat-stable cytosolic factor that promotes glucocorticoid receptor binding to DNA is neither thioredoxin nor ribonuclease
(Elsevier, 1987-11)
Treatment of rat liver cytosol containing temperature-transformed [3H]dexamethasone-bound receptors at 0[deg]C with the sulfhydryl modifying reagent methyl methanethiosulfonate (MMTS) inhibits the DNA-binding activity of ...
Protein-carbohydrate interaction : III. Agar gel-diffusion studies on the interaction of concanavalin A, a lectin isolated from jack bean, with polysaccharides
(Elsevier, 1965-08)
Concanavalin A, a protein isolated from the jack bean (Canavalia ensiformis), has previously been shown to form a precipitate with glycogen and yeast mannan, and more recently with dextrans and amylopectin. Double-diffusion ...
Modification of the 5′ Terminus of Oligonucleotides for Attachment of Reporter and Conjugate Groups
(John Wiley & Sons, 2000-02)
Reporter and conjugate groups can be added directly to the 5′ terminus of oligonucleotides by appropriate modification. Conjugate groups can be used to increase the affinity of complementary strands, induce irreversible ...
Synthesis of potential antiprogestogens
(Elsevier, 1976-01)
Acylated derivatives of 17[alpha]-hydroxyprogesterone were prepared in order to test the hypothesis that dialkylamino alkyl moieties have the effect of transforming progestogens into antiprogestogens. This approach has ...
Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide
(Elsevier, 1989)
Previous studies have demonstrated that a number of membrane-active agents are capable of binding to the surface of polymorphonuclear leukocytes (PMN) resulting in an augmentation of superoxide anion and hydrogen peroxide ...
Transferrin: A potential source of iron for oxygen free radical-mediated endothelial cell injury
(Elsevier, 1992-04)
The ability of transferrin to potentiate oxygen free radical-mediated endothelial cell injury was assessed. 51Cr-labeled endothelial cells derived from rat pulmonary arteries (RPAECs) were incubated with hydrogen peroxide ...