Now showing items 21-30 of 127
Collagen Cross-linking as a Determinant of Bone Quality: The Importance of Cross-linking to Mechanical Properties as Explored by Cross-link Inhibition and Exercise.
(2014)
Bone mineral density (BMD) and mass are primary clinical measures of fracture risk but do not fully describe bone quality. The organic matrix also contributes to bone mechanical properties and is stabilized by enzymatically ...
Adsorption of catechol and comparative solutes on hydroxyapatite
(Wiley Subscription Services, Inc., A Wiley Company, 2003-08-15)
Contemporary medical and dental adhesives often have difficulty sticking to wet surfaces or weaken with long-term exposure to water. Substantial research has been dedicated to finding a means of achieving adhesion in an ...
Magnetic Resonance Imaging Guidance of Histotripsy Therapy.
(2016)
Histotripsy is a cavitation based surgical therapy that transmits high amplitude acoustic pulses into a tissue target to stimulate the formation of energetic clouds of microbubbles. These microbubble clouds then exert a ...
Injectable microparticle–gel system for prolonged and localized lidocaine release. II. in vivo anesthetic effects
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocols for postoperative pain are beset by either the short duration of the anesthetic effect or requirement of hospitalization of the patients. We reported herein a novel treatment by applying to the ...
Surface modification of neural recording electrodes with conducting polymer/biomolecule blends
(John Wiley & Sons, Inc., 2001-08)
The interface between micromachined neural microelectrodes and neural tissue plays an important role in chronic in vivo recording. Electrochemical polymerization was used to optimize the surface of the metal electrode ...
Externally Applied Cyclic Strain Regulates Localization of Focal Contact Components in Cultured Smooth Muscle Cells
(Kluwer Academic Publishers-Plenum Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 2002-07)
Mechanical signals are critical regulators of cellular gene expression, yet little is understood of the mechanism whereby cells sense mechanical forces. In this study we have tested the hypothesis that mechanical strain ...
An Implantable Microsystem for Tonometric Blood Pressure Measurement
(Kluwer Academic Publishers; Springer Science+Business Media, 2001-12)
This paper presents an implantable microsystem for tonometric blood pressure measurement in small animals. The microsystem consists of four major components: (1) a titanium base for supporting a pressure sensor and an ...
Chondrocyte Differentiation is Modulated by Frequency and Duration of Cyclic Compressive Loading
(Kluwer Academic Publishers-Plenum Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 2001-06)
As part of a program of research aimed at determining the role of mechanical forces in connective tissue differentiation, we have developed a model for investigating the effects of dynamic compressive loading on chondrocyte ...
Microtubular architecture of biodegradable polymer scaffolds
(John Wiley & Sons, Inc., 2001-09-15)
It is a relatively new approach to generate tissues with mammalian cells and scaffolds (temporary synthetic extracellular matrices). Many tissues, such as nerve, muscle, tendon, ligament, blood vessel, bone, and teeth, ...
Micropatterned Structures for Studying the Mechanics of Biological Polymers
(Kluwer Academic Publishers; Springer Science + Business Media, Inc., 2005-03)
Studying the mechanics of nanometer-scale biomolecules presents many challenges; these include maintaining light microscopy image quality and avoiding interference with the laser used for mechanical manipulation, that is, ...