Now showing items 31-40 of 127
The Synthesis and Testing of Anti-Cancer Therapeutic Nanodevices
(Kluwer Academic Publishers; Springer Science+Business Media, 2001-03)
Nanotechnology provides the sized materials that can be synthesized and function in the same general size range and Biologic structures. We have attempted to develop forms of anticancer therapeutics based on nanomaterials. ...
Microfluidic systems: A new toolbox for pluripotent stem cells
(WILEY‐VCH Verlag, 2013-02)
Conventional culture systems are often limited in their ability to regulate the growth and differentiation of pluripotent stem cells. Microfluidic systems can overcome some of these limitations by providing defined growth ...
Engineering Systems to Study Cancer Metastasis.
(2015)
Metastasis causes most late relapses and fatalities from cancer. Investigating mechanisms of metastasis and designing therapies to limit metastatic disease are challenging due to difficulties studying key events that occur ...
Development and Manufacturing of Scaffold-less Constructs for Tendon/Ligament Repair.
(2014)
Soft tissues, such as rotator cuff tendons and the anterior cruciate ligament (ACL), integrate with the subchondral bone through a complex multi-tissue interface that functions to minimize the formation of stress concentrations ...
Smart HIV Testing System
(Kluwer Academic Publishers-Plenum Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 2005-06)
The quick HIV testing method called “MiraWell Rapid HIV Test” uses a specialized testing kit to determine whether an individual’s blood is contaminated with the HIV virus or not. When a drop of blood is placed on the center ...
Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems.
(2010)
Characterization and control of heterogeneous distributions of nanoparticle-ligand components are major design challenges for nanoparticle-based platforms. This dissertation begins with an examination of poly(amidoamine) ...
Tumor Necrosis Factor-Regulated Granuloma Formation in Tuberculosis: Multi-Scale Modeling and Experiments.
(2012)
Tuberculosis is a deadly infectious disease caused by Mycobacterium tuberculosis (Mtb). Multiple immune factors control host responses to Mtb infection, including the formation of granulomas in the lung, which are aggregates ...
Direct Measurement of Mammalian Axonemal Dynein's Motor Activity.
(2010)
Flagella and cilia play critical roles in mammalian and other eukaryotic life by providing propulsion for swimming cells and moving fluids across tissue surfaces. Flagellar/ciliary bending is caused by the sliding of doublet ...
Multi-spectral Dual Axes Confocal Endomicroscope with Vertical Cross-sectional Scanning for In-vivo Targeted Imaging of Colorectal Cancer
(2014)
Pathologists review histology cut perpendicular to the tissue surface or in the vertical cross-section (XZ-plane) in order to visualize the normal or abnormal differentiation patterns. The epithelium of hollow organs, such ...
Development and characterization of a canine oral mucosa equivalent in a serum-free environment
(Wiley Subscription Services, Inc., A Wiley Company, 2004-10-01)
The objectives of this study were to develop a serum-free system for culturing canine oral keratinocytes, the construction and characterization of a canine ex vivo produced oral mucosa equivalent (EVPOME), and transduction ...