Now showing items 3451-3460 of 3525
Direct comparison of Eulerian–Eulerian and Eulerian–Lagrangian simulations for particle‐laden vertical channel flow
(John Wiley & Sons, Inc., 2020-07)
Particle‐laden flows in a vertical channel were simulated using an Eulerian–Eulerian, Anisotropic Gaussian (EE‐AG) model. Two sets of cases varying the overall mass loading were done using particle sizes corresponding to ...
FRACPRED- 2D- PRM: A Fraction Prediction Algorithm- Assisted 2D Liquid Chromatography- Based Parallel Reaction Monitoring- Mass Spectrometry Approach for Measuring Low- Abundance Proteins in Human Plasma
(Wiley Periodicals, Inc., 2020-12)
Multidimensional fractionation- based enrichment methods improve the sensitivity of proteomic analysis for low- abundance proteins. However, a major limitation of conventional multidimensional proteomics is the extensive ...
Rapid microsphere‐assisted peptide screening (MAPS) of promiscuous MHCII‐binding peptides in Zika virus envelope protein
(John Wiley & Sons, Inc., 2020-03)
Despite promising developments in computational tools, peptide‐class II MHC (MHCII) binding predictors continue to lag behind their peptide‐class I MHC counterparts. Consequently, peptide–MHCII binding is often evaluated ...
Control of Stereoselectivity in Diverse Hapalindole Metabolites is Mediated by Cofactor‐Induced Combinatorial Pairing of Stig Cyclases
(Wiley Periodicals, Inc.Academic Press, 2020-05-18)
Stereospecific polycyclic core formation of hapalindoles and fischerindoles is controlled by Stig cyclases through a three‐step cascade involving Cope rearrangement, 6‐exo‐trig cyclization, and a final electrophilic aromatic ...
Semiclassical transition state theory/master equation kinetics of HO + CO: Performance evaluation
(World ScientificWiley Periodicals, Inc., 2020-12)
Previously, master equation (ME) simulations using semiclassical transition state theory (SCTST) and high‐accuracy extrapolated ab initio thermochemistry (HEAT) predicted rate constants in excellent agreement with published ...
Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods
(Wiley‐VCH, 2020-02-21)
Exploiting Imine Photochemistry for Masked N‐Centered Radical Reactivity
(CRC PressWiley Periodicals, Inc., 2019-12-19)
This report details the development of a masked N‐centered radical strategy that harvests the energy of light to drive the conversion of cyclopropylimines to 1‐aminonorbornanes. This process employs the N‐centered radical ...
The Need for and Path to Harmonized Life Cycle Assessment and Techno‐Economic Assessment for Carbon Dioxide Capture and Utilization
(National Academies PressWiley Periodicals, Inc., 2020-11)
Directed evolution methods for overcoming trade‐offs between protein activity and stability
(John Wiley & Sons, Inc., 2020-03)
Engineered proteins are being widely developed and employed in applications ranging from enzyme catalysts to therapeutic antibodies. Directed evolution, an iterative experimental process composed of mutagenesis and library ...
Magnetic Alignment of Polymer Macro‐Nanodiscs Enables Residual‐Dipolar‐Coupling‐Based High‐Resolution Structural Studies by NMR Spectroscopy
(Wiley Periodicals, Inc., 2019-10-14)
Experimentally measured residual dipolar couplings (RDCs) are highly valuable for atomic‐resolution structural and dynamic studies of molecular systems ranging from small molecules to large proteins by solution NMR ...