Now showing items 111-120 of 3162
Synthesis of metabolism-resistant substrates for the transport system for cationic amino acids; their stimulation of the release of insulin and glucagon, and of the urinary loss of amino acids related to cystinuria
(Elsevier, 1973-04-16)
Several amino acids have been synthesized as model transport substrates building on the piperidine and cyclohexane rings. Only when the distal N atom is part of an unambiguously cationic structure are these compounds ...
Soluble cytochrome b5 from human erythrocytes
(Elsevier, 1972-07-12)
1. A hemeprotein with properties similar to microsomal cytochrome b5 has been detected in the supernatant fraction of hemolysates of human, beef, and rabbit erythrocytes. A method has been developed for determining the ...
A direct-elution technique for the recovery of thin-layer samples
(Elsevier, 1978-01)
An elution technique is described which permits the recovery of samples from flexible thin-layer chromatograms without removal of the layer from the plate. This simple method avoids many of the problems associated with ...
Determination of Binding Mode: Intercalation
(Academic PressWiley Periodicals, Inc., 2000-02)
A small molecule can be assumed to bind to DNA by intercalation between base pairs if it causes lengthening and unwinding of the DNA helix and undergoes changes in its spectral properties, such as DNA‐induced hypochromism ...
Estimation of adsorbed anion charge density from the electrode charge-potential relationship
(Elsevier, 1967)
A correlation, based upon available data for a number of electrolytes at 0.1 and 1.0 N concentrations, may permit adsorbed anion charge densities to be estimated as a function of electrode potential by comparing the ...
Early events of Bacillus anthracis germination identified by time-course quantitative proteomics
(WILEY-VCH Verlag, 2006-10)
Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, including the spore coat. Here, we examine the temporal changes that occur ...
Cellular Delivery of Locked Nucleic Acids (LNAs)
(Wiley Periodicals, Inc., 2002-06)
Locked nucleic acids (LNAs) are RNA derivatives that have an O‐methylene linkage between the 2 and 4 positions of the ribose. This leads to exceptionally high‐affinity binding to complementary sequences. They are synthesized ...
A new two-site model for hydroxyapatite dissolution in acidic media
(Elsevier, 1978-11)
A physical model featuring two distinct types of dissolution sites for hydroxyapatite (HAP) crystals is presented. One of these sites (site No. 1) is associated with dissolution along c axis dislocations of HAP crystals ...