Now showing items 11-20 of 382
Proteomics FASTA Archive and Reference Resource
(WILEY-VCH Verlag, 2008-05)
A FASTA file archive and reference resource has been added to ProteomeCommons.org. Motivation for this new functionality derives from two primary sources. The first is the recent FASTA standardization work done by the Human ...
Synthesis of flexible ligands for assembling two metals in close proximity. Magnetic, electrochemical and spectral properties of binuclear copper (II) complexes with different exogenous bridging motifs
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-04)
Binuclear Cu II complexes having new flexible heptadentate ligands 2,6-bis{[bis(3,3′- N , N -dimethylaminopropyl)amino]methyl}-4-bromophenol [HL 1 ], 2,6-bis(3,3′- N , N -dimethylaminopropyl)amino]methyl}-4-methylphenol ...
Key Experimental Approaches in DNA Nanotechnology
(Alan R. LissWiley Periodicals, Inc., 2002-06)
DNA nanotechnology combines unusual DNA motifs with sticky‐ended cohesion to build polyhedral objects, topological targets, nanomechanical devices, and both crystalline and aperiodic arrays. The goal of DNA nanotechnology ...
Probing RNA Structure with Chemical Reagents and Enzymes
(Wiley Periodicals, Inc., 2000-02)
This unit provides thorough coverage of the most useful chemical and enzyme probes that can be used to examine RNA secondary and tertiary structure. Footprinting methods are presented using dimethyl sulfate, diethyl ...
Role of conformational dynamics in sequence-specific autoantibody•ssDNA recognition
(Wiley Subscription Services, Inc., A Wiley Company, 2007-04-05)
11F8 is a sequence-specific monoclonal anti-ssDNA autoantibody isolated from a lupus prone mouse that forms pathogenic complexes with ssDNA, resulting in kidney damage. Prior studies show that specificity is mediated by a ...
Characterization of nucleic acid higher order structure by gas-phase H/D exchange in a quadrupole-FT-ICR mass spectrometer
(Wiley Subscription Services, Inc., A Wiley Company, 2009-04)
Nucleic acid higher order structure is of intense interest in antisense and antigene strategies toward novel chemotherapeutic agents. Understanding how structural characteristics affect solution-phase properties is essential ...
Oligoribonucleotides with 2′‐O‐(tert‐Butyldimethylsilyl) Groups
(Wiley Periodicals, Inc.IRL Press,, 2000-07)
The chemical synthesis of oligoribonucleotides on solid support is routinely performed via the phosphoramidite method. However, the additional 2‐OH function of the ribofuranosyl sugar requires suitable protection during ...
Determination of Binding Mode: Intercalation
(Academic PressWiley Periodicals, Inc., 2000-02)
A small molecule can be assumed to bind to DNA by intercalation between base pairs if it causes lengthening and unwinding of the DNA helix and undergoes changes in its spectral properties, such as DNA‐induced hypochromism ...
Early events of Bacillus anthracis germination identified by time-course quantitative proteomics
(WILEY-VCH Verlag, 2006-10)
Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, including the spore coat. Here, we examine the temporal changes that occur ...