Now showing items 1151-1160 of 1179
Personalized and Tissue-Specific Melt Electrowritten Scaffolds for Coordinated Regeneration of Soft and Hard Periodontal Tissues
(2021)
Periodontitis is a chronic inflammatory, bacteria-triggered disorder affecting nearly half of American adults. If left untreated, it leads to severe destruction of the periodontium, i.e., the alveolar bone, periodontal ...
Mechanisms of Complex Tissue Regeneration and the Functional Outcomes of Craniofacial Dysmorphology
(2020)
There is a clinical need to restore craniofacial tissues affected by disorders of traumatic and/or congenital etiology. Effective therapies within this specialized region must achieve anatomic regeneration while also ...
The Role of Collagen Cross-linking in Craniofacial and Long Bone Mineralization and Healing
(2021)
Compromised collagen and mineral can lead to decreases in bone quantity and quality in a variety of diseases that differentially affect craniofacial and long bones. Since bone is a composite - with mineral lending stiffness ...
Perivascular Niche and Self-renewal of Dental Pulp Stem Cells
(2020)
Interactions with the microenvironment modulate the fate of stem cells in perivascular niches in tissues (e.g. bone) and organs (e.g. liver). However, the functional relevance of the molecular crosstalk between endothelial ...
The Function and Regulation of LIM Domain Mineralization Protein (LMP) in Periodontal Ligament Progenitor Cells.
(2010)
New methodologies to target and deliver osteogenic factors offer significant potential for craniofacial tissue engineering. LIM domain mineralization protein (LMP) appears to be such a candidate for periodontal bone ...
Determining the Structural and Functional Characteristics of Enamelin in Enamel Formation.
(2010)
Enamelin (Enam) is essential for proper dental enamel formation. In Enam null mice the mineralization front associated with the secretory surface of the ameloblast membrane fails to initiate and elongate enamel mineral ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Ameloblastin: Evolution, Structure and Function in Enamel Formation.
(2009)
Dental enamel formation is dependent upon the secretion of three enamel proteins: amelogenin, enamelin, and ameloblastin (Ambn). These proteins contribute to a mineralization front on the secretory surface of ameloblasts. ...
Crosstalk between Endothelial Cells and Tumor Cells in Head and Neck Cancer
(2009)
Tumor angiogenesis is necessary for cancer progression and requires active interaction between endothelial cells and tumor cells. It is well established that cancer cells secrete angiogenic factors to recruit and sustain ...
Regulation of Bone Formation and Pathology by Local Actions of Leptin in the Bone Marrow.
(2011)
Site-specific adipose content of the bone marrow has been noted since the inclusion
of meat into the hominid diet, evidenced by marrow removal from ungulate limb
bones, 2.6 million years ago. Association between marrow fat ...