Now showing items 831-840 of 859
Bisantrene (NSC 337766) (CL 216,942) in advanced breast cancer
(Springer-Verlag, 1984-10)
Bisantrene (NSC 337766) is an anthracenedicarboxaldehyde hydrazone demonstrating a wide spectrum of activity in animal tumor model systems with no evidence of cardiotoxicity or alopecia, in contrast to doxorubicin. ...
A general procedure for mild and rapid reduction of aliphatic and aromatic nitro compounds using ammonium formate as a catalytic hydrogen transfer agent
(Elsevier, 1984)
Various aliphatic and aromatic nitro compounds were selectively and rapidly reduced to their corresponding amino derivatives in very good yield using anhydrous ammonium formate as a catalytic hydrogen transfer agent.
A chemical approach to solving bridging phenomena in steroid radioimmunoassays
(Elsevier, 1981-08)
Steroid radioimmunoassays (RIA) employ antibodies raised against a carrier protein-steroid conjugate. Individual antibodies may recognize the steroid, the protein or the chemical bridge used to Join them together. Use of ...
The conformation of alkyl sulfoxides
(John Wiley & Sons, Inc., 1981)
Parameters for sulfoxides used in force field MM1 were modified to be incorporated into force field MM2. The conformations of ten alkyl sulfoxides were then calculated using MM2 with these new parameters. The alkyl groups ...
Regional processing of the N- and C-terminal domains of proopiomelanocortin in monkey pituitary and brain
(Elsevier, 1988-04)
The total content and extent of processing of the [gamma]3MSH and [beta]-endorphin-containing N- and C-terminal domains of proopiomelanocortin were determined in the anterior and intermediate lobes of the pituitaries and ...
A reagent for covalently attaching biotin to proteins via a cleavable connector arm
(Elsevier, 1982-10-01)
The preparation of a reagent which can be used to attach biotin to proteins via a cleavable connector arm is described. The reagent, 3-(4-(N-biotinoyl-6-aminocaproyloxy)phenyl)propionic acid N-hydroxysuccinimide ester ...
A practical large scale chemical synthesis of chiral glycines
(Elsevier, 1988)
(R)- and (S)-[2-2H]glycine of high chiral purity were synthesized in large quantities in [approximate] 40% overall yield from readily available starting materials via a totally chemical procedure. Reduction of either ...
Implicit-adsorbate model for apparent anomalies with organic adsorption on natural adsorbents
(American Chemical Society, 1984-12)
High-performance liquid chromatographic determination of ibuprofen and its major metabolites in biological fluids
(Elsevier, 1982-11-12)
A sensitive and selective high-performance liquid-chromatographic assay for ibuprofen and its major metabolites in biological fluids is described. To ensure good chromatographic separation the drug and metabolites were run ...
Determination of the glucosidase-stimulating proteins by competitive enzyme-linked immunoassay
(Elsevier, 1984-10)
A procedure for the immunoassay of cohydrolase sphingolipid-I in mouse tissue is described. This cohydrolase (actually a mixture of at least four related proteins) stimulates or activates the [beta]-glucosidase which ...