Now showing items 111-120 of 184
Structure of the human cytochrome c oxidase subunit Vb gene and chromosomal mapping of the coding gene and of seven pseudogenes
(Elsevier, 1991-05)
Subunit Vb of mammalian cytochrome c oxidase (COX; EC 1.9.3.1) is encoded by a nuclear gene and assembled with the other 12 COX subunits encoded in both mitochondrial and nuclear DNA. We have cloned the gene for human COX ...
Sequence-tagged sites (STSs) for a set of mapped markers on chromosome 21
(Elsevier, 1992-10)
Sequence tagged sites (STSs) have been proposed as a "common language" for comparing physical and genetic maps of the human genome produced by a variety of techniques. We have produced 44 STSs from 38 mapped loci on human ...
A 13 base pair deletion in exon 1 of HPRT Illinois forms a functional GUG initiation codon
(Springer-Verlag, 1994-03)
More than 50 mutations in the human hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus have been described, yet only 2 alter the AUG initiation codon. One, variant HPRT 1151 , results in Lesch-Nyhan syndrome (LNS), ...
Familial transmission of alcohol use: V. Drinking patterns among spouses, Tecumseh, Michigan
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1992-01)
This study examined concordance and discordance of self-reported alcohol consumption in 184 spouse pairs drawn from a representative sample of the Tecumseh, MI community. A significant association (tau B=.57, p <.001) ...
Sequence-tagged sites (STSs) spanning 4p16.3 and the Huntington disease candidate region
(Elsevier, 1992-05)
The generation of sequence-tagged sites (STSs) has been proposed as a unifying approach to correlating the disparate results generated by genetic and various physical techniques being used to map the human genome. We have ...
A class I jumping clone places the HLA-G gene approximately 100 kilobases from HLA-H within the HLA-A subregion of the human MHC
(Elsevier, 1991-08)
By the combination of cosmid cloning, chromosomal jumping, and pulsed-field gel electrophoresis (PFGE), we have fine-mapped the HLA-A subregion of the human major histocompatibility complex (MHC). Through the isolation of ...
An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
Three common alleles, ɛ 2 , ɛ 3 , and ɛ 4 , of the gene coding for apolipoprotein E (apoE) have been identified as predictors of interindividual variation in measures of lipid and lipoprotein metabolism, and ultimately ...
Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: Localization of the CDC11 gene product and the timing of events at the budding site
(Wiley Subscription Services, Inc., A Wiley Company, 1991)
The Saccharomyces cerevisiae CDC3 , CDC10 , CDC11 , and CDC12 genes encode a family of homologous proteins that are not closely related to other known proteins [Haarer BK, Ketcham SR, Ford SK, Ashcroft DJ, and Pringle ...
Depression and parental bonding: Cause, consequence, or genetic covariance?
(Wiley Subscription Services, Inc., A Wiley Company, 1994)
It is shown how information on the direction of causation between variables may be obtained from a cross‐sectional study of pairs of relatives. This method is applied to the study of the relationship between ratings of ...
Related subunits of NF-[kappa]B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2
(Elsevier, 1992-06)
The chromosomal locations of the human genes NFKB1 and NFKB2, which encode two alternative DNA binding subunits of the NF-[kappa]B complex, p105 and p49/p100, respectively, have been determined. p105 was assigned to ...