Now showing items 61-70 of 184
Expressed sequence tags and chromosomal localization of cDNA clones from a subtracted retinal pigment epithelium library
(Elsevier, 1992-07)
Expressed sequence tags (ESTs) provide useful molecular landmarks for physical mapping and identify the position of an expressed region in the genome. The use of subtracted cDNA libraries enriched for tissue-specific genes ...
Psychiatric comorbidity of smoking and nicotine dependence
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-03)
Recent epidemiologic studies have revealed that comorbidity of psychiatric disorders is far more pervasive than previously suspected. Strong associations have been reported between specific substance use disorders and ...
Control of Enterococcus faecalis sex pheromone cAD1 elaboration: Effects of culture aeration and pAD1 plasmid-encoded determinants
(Elsevier, 1991-05)
Aeration of plasmid-free Enterococcus faecalis strains resulted in an 8- to 16-fold decrease in sex pheromone cAD1 activity in culture filtrates. Levels of two unrelated pheromones, cPD1 and cAM373, were unaffected by ...
Duchenne muscular dystrophy
(Elsevier, 1991-06)
Progress in understanding the role of dystrophin raises promising hopes for a treatment for Duchenne muscular dystrophy. In addition, great improvements have been made in the ability to diagnose this disease using simple ...
Post-meiotic gene expression
(Elsevier, 1990)
Evolutionary arguments and well-designed experiments (based on false premises, however) bad suggested that post-meiotic gene expression did not occur in animals. The technique of molecular genetics have now clearly ...
Nonsense mutations at Arg-1947 in two cases of familial neurofibromatosis type 1 in Japanese
(Springer-Verlag, 1994-01)
We report two familial cases of NF1 presenting as C to T transitions changing an Arg-1947 codon to a stop codon. In one of the two families, cosegregation of the mutation with NF1 was demonstrated, indicating this mutation ...
Development of a sensitive, highly controlled assay for molecular detection of the Philadelphia chromosome in patients with chronic myelogenous leukemia
(Elsevier, 1994)
The Philadelphia chromosome (Ph1), present in [ges]95% of chronic myelogenous leukemia (CML) patients, is a well-characterized translocation that results in a unique chimeric gene product (BCR/ABL) with transforming ...
Bacteriophage T4 ribonucleoside diphosphate reductase: on the defect causing decreased formation of the [beta]293 subunit encoded by the nrdB93 mutant gene
(Elsevier, 1994-05-03)
Bacteriophage T4 ribonucleoside diphosphate reductase is composed of two proteins, [alpha]2 and [beta]2, encoded by the nrdA and nrdB genes, respectively. The expression of nrdB is the limiting factor for the assembly of ...