Now showing items 81-90 of 184
Plasmids for recombination-based screening
(Elsevier, 1991-09-30)
To facilitate recombination-based screening, we constructed the ColE1-based plasmid, [pi]G4, that confers chloramphenicol resistance, contains a polylinker with multiple unique restriction enzyme recognition sequences, and ...
cDNA cloning of the type 1 neurofibromatosis gene: Complete sequence of the NF1 gene product
(Elsevier, 1991-12)
Von Recklinghausen neurofibromatosis, or type 1 neurofibromatosis (NF1), is a common autosomal dominant disorder characterized by abnormalities in multiple tissues derived from the embryonic neural crest. Portions of the ...
Two subfamilies of murine retrotransposon ETn sequences
(Elsevier, 1990-02-14)
Early transposon (ETn) elements are 5.7-kb retrotransposons found in the murine genome. We have sequenced large portions of two ETn elements that have apparently transposed within the DNA of a murine myeloma cell line, ...
Multicolor FISH Mapping of YAC Clones in 3p14 and Identification of a YAC Spanning both FRA3B and the t(3;8) Associated with Hereditary Renal Cell Carcinoma
(Elsevier, 1994-07-15)
Human chromosome band 3p14 contains two tightly linked cytogenetic markers of broad interest, FRA3B and the t(3;8) breakpoint associated with hereditary renal cell carcinoma (RCC). The common fragile site at 3p14.2 (FRA3B) ...
A B2 Repeat Insertion Generates Alternate Structures of the Mouse Muscle [gamma]-Phosphorylase Kinase Gene
(Elsevier, 1993-04)
A variety of cDNA and genomic clones for the [gamma]-subunit of mouse muscle phosphorylase kinase (Phk-[gamma]M) have been isolated and characterized. The murine gene for Phk-[gamma]M (Phkg) exhibits multiple transcription ...
Insertional mutation of `classical' and novel genes in transgenic mice
(Elsevier, 1992-10)
Approximately 5% of established transgenic lines carry insertional mutations. The mutated genes may be directly isolated using the transgene DNA as a molecular probe. These mutants provide useful models of human inherited ...
Metanephric rat-mouse chimeras to study cell lineage of the nephron
(John Wiley & Sons, Inc., 1999)
The nephron is derived from the ureteric bud and metanephric mesenchyme and develops into a complex epithelial structure with a wide variety of phenotypes along its length. This segmental variation in expression of molecules ...