Now showing items 251-260 of 265
Interaction between [3H]ethylketocyclazocine and [3H]etorphine and opioid receptors in membranes from rat brain a kinetic analysis
(Elsevier, 1986-04)
Scatchard analysis of the binding to opioid receptors of pHlethylketocyclazocine ([3H]EKC) and [3H]etorphine at equilibrium yielded biphasic plots and computer fitting of the data resulted in a minimal model of two independent ...
Immunocytochemistry of sequence-related neuropeptides in Drosophila
(Elsevier, 1993-06)
Based on structure, activity, and expression, the Drosophila drosulfakinin I peptide (DSK I; FDDY(OSO3H)GHMRFamide) is similar to the vertebrate peptide, cholecystokinin.1 Dromyosuppressin (DMS; TDVDHVFLRFamide) is an ...
Stress induced facilitation of opiate catalepsy in the rat
(Elsevier, 1980)
1. 1. Adult male Sprague-Dawley rats were injected with a standard low dose of opiate (10 mg/kg of morphine sulfate).2. 2. Experimental subjects received one of two stressful procedures (tail pinch, floor cooling) while ...
Chronic use of benzodiazepines and psychomotor and cognitive test performance
(Springer-Verlag, 1986-04)
The performance of 43 long-term users (average = 5 years) of benzodiazepine (BZ) medications was examined on a battery of behavioral tasks, cognitive tests, and subjective mood rating scales. The performance of the chronic ...
Sites of synthesis of chromogranins A and B in the human brain
(Elsevier, 1992-04)
The sites of synthesis of the chromogranins A and B, and their potential processed peptides, were examined by quantitating the levels of chromogranin A and B mRNA in various regions of the human brain by Northern blot ...
Naltrexone reduces ethanol- and sucrose-reinforced responding in rhesus monkeys
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
These experiments evaluated the ability of naltrexone (NTX) to reduce selectively oral and IV ethanol-reinforced responding, and examined the ethanol-NTX interaction in terms of the competitive opioid antagonist property ...
Increased sensitivity of adenylate cyclase activity in the striatum of the rat to calmodulin and GppNHp after chronic treatment with haloperidol
(Elsevier, 1986-06)
Chronic treatment of rats with haloperidol causes behavioral supersensitivity to dopaminergic agonists and an increase in the sensitivity of adenylate cyclase activity in the striatum to stimulation by dopamine. In this ...
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-02)
Rationale : By acting on peripheral opioid receptors, opioid agonists can attenuate nociceptive responses induced by a variety of agents. Objectives : This study was conducted to characterize capsaicin-induced thermal ...
Low-Flow Push-Pull Perfusion for Measuring Neurotransmitters with High Spatial and Temporal Resolution within the Living Brain.
(2013)
Low-flow push-pull perfusion is a technique for measuring neurotransmitters within the brain with ~200 μm resolution. Activity of neurotransmitters can vary on this size scale; therefore, low-flow push-pull may offer new ...