Now showing items 291-300 of 336
Expression, Purification, and Binding Properties of Human Cellular Retinoic Acid-Binding Protein Type I and Type II
(Elsevier, 1993-02-01)
Human cellular retinoic acid-binding protein (CRABP) type I and type II were expressed in Escherichia coli from cloned cDNAs. Expressed proteins were purified by gel filtration and ion-exchange chromatography, resulting ...
Diurnal Regulation of Glucocorticoid Receptor and Mineralocorticoid Receptor mRNAs in Rat Hippocampus
(Elsevier, 1993-04)
The present studies were undertaken to determine whether hippocampal glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) biosynthesis, as inferred from mRNA expression, exhibit diurnal patterns of activation ...
Immunohistochemical localization of the kappa1 opioid receptors
(Elsevier, 1994-11-10)
Using antibodies generated to the C-terminal 41 amino acids of the cloned rat kappa receptor, the present study examines the distribution of the kappa1 receptor-like immunoreactivity (li) using immunohistochemical techniques. ...
Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
(Elsevier, 1993-12)
Repeated, intermittent treatment of rats with amphetamine results in a sensitization of locomotor and stereotyped behaviors that is accompanied by an enhancement in stimulus-induced dopamine release. Increased phosphorylation ...
Synthesis of 6- or 7-substituted 1,2,3,4-tetrahydroisoquinoline- 3-carboxylic acids
(Kluwer Academic Publishers; Springer Science+Business Media, 1999-03)
A straightforward approach for the synthesis of several new, aryl-substituted derivatives of the conformationally constrained phenylalanine analogue 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) is described. Tic, ...
Bone Marrow Transplantation Demonstrates That Carbonic Anhydrase II Deficiency Limited to Bone Marrow-Derived Cells Affects Ammonium Chloride Tolerance in Mice
(Elsevier, 1994-02)
Bone marrow transplantation (BMT) in mice was utilized to determine the relative importance of carbonic anhydrase II (CA II) deficiency in blood compared to kidney in the pathogenesis of the ammonium chloride intolerance ...
Age-Associated Decline in IL-4 Production by Murine T Lymphocytes in Extended Culture
(Elsevier, 1993-10-01)
Aging leads to an increase in the proportion of cells that have the surface phenotype (CD45RBIo, CD44bi) characteristic of memory T lymphocytes and also to a decline in both the production of IL-2 and the response to this ...
The development of live attenuated cold-adapted influenza virus vaccine for humans
(John Wiley & Sons, Ltd., 1999-10)
A procedure to attenuate live influenza virus of type A and type B was developed using adaptation of the virus to grow at 25°C (cold adaptation; ca). Through a series of stepwise passages, two stable mutants were obtained ...