Now showing items 1391-1400 of 1412
The future of basic science research into a leading cause of disability and death
(Wiley Periodicals, Inc.The Atlantic, 2022-10)
The Role of Leptin Action in States of Obesity
(2020)
Over the last century, the United States has experienced a shift from underweight malnutrition maladies to obesity-associated complications. Today, over 70% of US adults are overweight and are at increased risk for various ...
Computer Simulation of a Nitric Oxide-Releasing Catheter with a Novel Stable Convection-Diffusion Equation Solver and Automatic Quantification of Lung Ultrasound Comets by Machine Learning
(2020)
Biological transport processes often involve a boundary acting as separation of flow, most commonly in transport involving blood-contacting medical devices. The separation of flow creates two different scenarios of mass ...
Investigation of Clinical Characteristics of Men with Chronic Unexplained Orchialgia
(2017)
Chronic pain is a public health issue in the United States. Men with chronic unexplained orchialgia (CUO) are an understudied population, with significant knowledge gaps regarding to demographics, etiology, and reliable ...
Negative regulation and immune effects of apoptotic cell clearance in the lung: SIRPa and miR34a.
(2014)
Apoptotic cell clearance (efferocytosis) is the essential biological process by which dead cells, called apoptotic cells (AC), are engulfed and recycled by living cells called phagocytes. This process is regulated by many ...
Meeting the Geriatric Care Needs of an Aging Population: Older Adult, Family Caregiver, and Provider Perspectives
(2020)
There is a critical need to ensure the provision of high-quality health care for a growing population of adults age 65 and older (older adults). Recent policy initiatives emphasize the need for a health care workforce that ...
Characterization of the function of the LMAN1 ER cargo receptor in vivo.
(2016)
Combined deficiency of coagulation factors V and VIII (F5F8D) is an autosomal recessive bleeding disorder caused by defects in LMAN1 or MCFD2, which form the only known mammalian secretory ER cargo-receptor. LMAN1/MCFD2 ...
Design and Testing Novel Wearable Instrumentation for Assessing Pelvic Floor Function and Exploring Continence Mechanisms
(2020)
Urinary incontinence (UI) and fecal incontinence (FI) affect 20% of North Americans, with a higher prevalence in women and the elderly. The prevention and treatment of these conditions unfortunately leaves much to be ...
The Role of Kruppel-like Factor 11 in Vascular Homeostasis
(2021)
Krüppel-like factors (KLFs) are transcription factors containing three conserved zinc finger motifs in the carboxy-terminus and have shown associations with many diseases, including cancer, diabetes, and vascular disorders. ...
The Particulars of Particulate Matter Induced Myofibroblast Differentiation
(2022)
Particulate matter (PM) has long been appreciated as a biologically significant component of air pollution that has major impacts on public health. Exposure to PM less than 2.5 µm in diameter (PM2.5) is associated with ...