Now showing items 21-30 of 54
Protein Kinase Inhibitors Block Neurite Outgrowth from Explants of Goldfish Retina
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1997-10)
A role for protein phosphorylation in the process of neurite outgrowth has been inferred from many studies of the effects of protein kinase inhibitors and activators on cultured neurotumor cells and primary neuronal cells ...
Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I
(Elsevier, 1992-08)
The Drosophila drosulfakinin (dsk) gene encodes the cholecystokinin homologues drosulfakinin-I (DSK-I) and drosulfakinin-II (DSK-II). The naturally occurring DSKI peptide was isolated from an extract of adult flies and its ...
Multiple steroid hormone levels in depressed patients and normal controls before and after exogenous ACTH
(Elsevier, 1991)
Forty depressed patients and 36 age- and sex-matched controls were given 250 [mu]g ACTH1-24 by bolus. Plasma steroid hormone levels were measured prior to and 60 min after ACTH administration. The depressed patients had ...
Continued search for the cellular signals that regulate regeneration of dopaminergic neurons in goldfish retina
(Elsevier, 1993-12-17)
Intraocular injections of low doses (0.7-1.4 mM estimated intraocular concentration) of 6-hydroxydopamine (6OHDA) selectively destroy dopaminergic neurons in the inner nuclear layer (INL) of goldfish retina, and they never ...
c-Myc Does Not Require Max for Transcriptional Activity in PC-12 Cells
(Elsevier, 1994-06)
The c-Myc proto-oncogene is a basic helix-loop-helix leucine zipper (b/HLH/LZ) protein that participates in cellular growth and differentiation. The expression of cMyc mRNA is rapidly induced by nerve growth factor (NGF) ...
Expression of erbA[alpha] and [beta] mRNAs in regions of adult rat brain
(Elsevier, 1990-03-26)
The proto-oncogenes erbAa and erbA[beta] together encode three functional thyroid hormone receptors (erbAol, [beta]1, and [beta]2), as well as two proteins (erbA[sigma] 2 and [alpha]3) that do not bind T3. The erbA[alpha]2 ...
[kappa]1 Receptor mRNA Distribution in the Rat CNS: Comparison to [kappa] Receptor Binding and Prodynorphin mRNA
(Elsevier, 1994-04)
Three opioid receptor types have been identified in the CNS and periphery that are referred to as [mu], [delta], and [kappa]. The present study examines the mRNA distribution of the [kappa]1 receptor in the rat brain and ...
Glutamate uptake system in the presynaptic vesicle: Glutamic acid analogs as inhibitors and alternate substrates
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1993-01)
A variety of naturally occurring amino acids, their isomers, and synthetic analogs were tested for their ability to inhibit uptake of [ 3 H]glutamate into presynaptic vesicles from bovine cerebral cortex. Strongest inhibition ...
Autoradiographic quantification of muscarinic cholinergic synaptic markers in bat, shrew, and rat brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
We employed radioligand binding autoradiography to determine the distributions of pre- and postsynaptic cholinergic radioligand binding sites in the brains of two species of bat, one species of shrew, and the rat. High ...
Molecular and electrophysiological characterization of a allelic variant of the rat [alpha]6 GABAA receptor subunit
(Elsevier, 1992-11)
A 1.45 kb DNA sequence encoding the rat [alpha]6 GABAA receptor subunit (nucleotides 33-1483) was clonedfrom a Sprague-Dawley rat brain cDNA library by PCR amplification. Dideoxy sequencing of two individual clones revealed ...