Now showing items 11-20 of 21
Pre dialysis of blood prime in continuous hemodialysis normalizes pH and electrolytes
(Springer-Verlag; IPNA, 2003-11)
In critically ill children weighing <10 kg, it is necessary to use blood as a priming solution for the extracorporeal continuous renal replacement therapy (CRRT) circuit before initiating CRRT to prevent hemodilution and ...
Isradipine treatment of hypertension in children: a single-center experience
(Springer-Verlag; IPNA, 2002-09)
Many children with hypertension, particularly those with new-onset hypertension related to glomerulonephritis, organ transplantation, or other forms of secondary hypertension, require treatment with a short-acting ...
Cyclosporine absorption profiles in pediatric kidney and liver transplant patients
(Springer-Verlag; IPNA, 2003-12)
Cyclosporine absorption profiling uses either the area under the concentration curve in the first 4 h post dose, AUC(0–4), or the concentration 2 h post dose (C2) to optimize immunosuppression in adult kidney and liver ...
Pediatric acute renal failure: outcome by modality and disease
(Springer-Verlag; IPNA - International Pediatric Nephrology Association New York, USA, 2001-12)
Two hundred and twenty-six children who underwent renal replacement therapy (RRT) from 1992 to 1998 were retrospectively reviewed. The mean age, at the onset of RRT, was 74±11.7 months and weight was 25.3±9.7 kg. RRT ...
Role of the tyrosine kinase JAK2 in signal transduction by growth hormone
(Springer-Verlag; IPNA - International Pediatric Nephrology Association New York, USA, 2000-06)
Chronic renal failure in children results in impaired body growth. This effect is so severe in some children that not only does it have a negative impact on their self-image, but it also affects their ability to carry out ...
No evidence for genotype/phenotype correlation in NPHS1 and NPHS2 mutations
(Springer-Verlag; IPNA, 2004-12)
Primary steroid-resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end-stage renal disease. In 26% of cases it is caused by recessive mutations in NPHS2 (podocin). ...
The use of mycophenolate mofetil suspension in pediatric renal allograft recipients
(Springer-Verlag; IPNA - International Pediatric Nephrology Association New York, USA, 2001-12)
Mycophenolate mofetil (MMF) is widely used to prevent acute rejection in adults after renal, cardiac, and liver transplantation. This study investigated the safety, tolerability, and pharmacokinetics of MMF suspension in ...
Calcium channel blockers: pharmacology and place in therapy of pediatric hypertension
(Springer-Verlag; IPNA - International Pediatric Nephrology Association New York, USA, 2000-11)
The calcium channel blockers (CCBs) are a diverse group of antihypertensive medications with variable pharmacokinetics and clinical effects. Although CCBs have been widely applied to the treatment of hypertensive children, ...
Pharmacokinetics of darbepoetin alfa in pediatric patients with chronic kidney disease
(Springer-Verlag; IPNA, 2002-11)
Darbepoetin alfa is a novel erythropoiesis-stimulating protein with a two- to threefold longer half-life than recombinant human erythropoietin (epoetin) in adult patients with chronic kidney disease (CKD). This randomized, ...
Neonatal hypertension: diagnosis and management
(Springer-Verlag; IPNA - International Pediatric Nephrology Association New York, USA, 2000-03)
Hypertension in the term or preterm neonate may be seen in up to 2% of all infants cared for in the modern neonatal intensive care unit. Although the definition of hypertension in this age group has not been completely ...