Now showing items 31-40 of 438
Squamous cell carcinoma of the vulva: Prognostic factors influencing survival
(Elsevier, 1991-11)
One hundred seventy-two cases of patients with squamous cell cancer of the vulva treated at the University of Michigan Medical Center from 1975 to 1988 are reported. The mean age was 66 years with a range of 21 to 101 ...
Cell surfaces and embryos: Expression of the F9 teratocarcinoma antigen in T-region lethal, other lethal, and normal pre-implantation mouse embryos
(Elsevier, 1980-12)
F9 teratocarcinoma antigen is expressed normally on embryos which are homozygous recessive for each of 4 mutations lethal in early development, including t12. Homozygosity for two post-implantation T-region developmental ...
Multiple Signaling Pathways are Activated During Insulin-like Growth Factor-I (IGF-I) Stimulated Breast Cancer Cell Migration
(Kluwer Academic Publishers; Springer, 2005-09)
In order to display the full metastatic phenotype, the cancer cell must acquire the ability to migrate. In breast cancer, we have previously shown that insulin-like growth factor I (IGF-I) enhances cell motility in the ...
Infection on a gynecologic oncology service
(Elsevier, 1990-05)
Little information is available pertaining to infectious morbidity in women with genital malignancy. To define the magnitude of this problem, all patients admitted to the gynecologic oncology services at the University of ...
Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons
(Elsevier, 1986-07)
Nerve growth factor (NGF) is a neuronotrophic protein. Its effects on developing peripheral sensory and sympathetic neurons have been extensively characterized, but it is not clear whether NGF plays a role during the ...
Mitogenic Activity of Growth Factors in the Human Endometrial Adenocarcinoma Cell Lines HEC-1-A and KLE
(Elsevier, 1993-06)
Endometrial adenocarcinoma is the most common gynecologic malignancy occurring in the United States. Evidence is accumulating that links peptide growth factors with malignant proliferation. Epidermal growth factor (EGF) ...
Gene expression of the insulin-like growth factors and their receptors in cultured human retinal pigment epithelial cells
(Elsevier, 1992-01)
Insulin-like growth factors I and II (IGF I and II) are polypeptides with both growth-promoting and insulin-like metabolic effects16,27. Immunoreactive IGF I is present in the retina14 and both IGF I and II are present in ...
Regulation of epidermal growth factor and insulin-like growth factor I receptors by estradiol and progesterone in normal and neoplastic endometrial cell cultures,
(Elsevier, 1990-09)
Growth factors are polypeptides which regulate cell proliferation through binding to specific receptor proteins. Normal and neoplastic human endometrium have been shown to express epidermal growth factor (EGF) and insulin-like ...
Coexistent squamous cell carcinoma and adenocarcinoma of the uterine cervix
(Elsevier, 1984-02)
The clinical and pathological features of 20 patients with coexistent squamous cell carcinoma and adenocarcinoma of the uterine cervix have been analyzed. Various combinations of in situ and invasive carcinomas were found. ...