Now showing items 1-10 of 46
The synthesis and chemistry of certain anthelmintic benzimidazoles
(Elsevier, 1990-04)
A basis for interest in the benzimidazole ring system as a nucleus from which to develop potential chemotherapeutic agents was established in the 1950s when it was found that 5,6-dimethyl-l-([alpha]-D-ribofuranosyl)benzimidazole ...
Cytomegalovirus infections in lung and hematopoietic cell transplant recipients in the Organ Transplant Infection Prevention and Detection Study: A multi‐year, multicenter prospective cohort study
(Wiley Periodicals, Inc., 2018-06)
BackgroundMost studies of post‐transplant CMV infection have focused on either solid organ or hematopoietic cell transplant (HCT) recipients. A large prospective cohort study involving both lung and HCT recipients provided ...
Adult patients with respiratory syncytial virus infection: impact of solid organ and hematopoietic stem cell transplantation on outcomes
(Wiley Periodicals, Inc., 2015-08)
BackgroundRespiratory syncytial virus (RSV) is a common community‐acquired pathogen responsible for a substantial disease burden in adults. We investigated the outcomes after RSV infection in hospitalized adults over a ...
Risk factors for recurrent C lostridium difficile infection in hematopoietic stem cell transplant recipients
(Wiley Periodicals, Inc., 2014-10)
Background Recurrent C lostridium difficile infection ( CDI ) represents a significant burden on the healthcare system and is associated with poor outcomes in hematopoietic stem cell transplant ( HSCT ) patients. Data ...
A case of Q fever after liver transplantation
(Wiley Periodicals, Inc., 2017-10)
Coxiella burnetii, the causative agent of Q fever, is a zoonosis that causes both acute and chronic disease in humans. Few cases have been reported in solid organ transplant recipients, and this case highlights the need ...
UL 54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease
(Wiley Periodicals, Inc., 2014-04)
We present a case of foscarnet ( FOS ) resistance arising from a UL 54 mutation after a short duration of FOS exposure, which has not been previously described in a stem cell transplant recipient, to our knowledge. We ...
Voriconazole is safe and effective as prophylaxis for early and late fungal infections following allogeneic hematopoietic stem cell transplantation
(Blackwell Publishing Inc, 2010-02)
Seventy-two patients undergoing allogeneic transplantation were treated with voriconazole (VOR) as antifungal prophylaxis starting from day −2 of transplantation and continuing until withdrawal of immunosuppression. Patients ...
High incidence of neoplasms in female NZB/NZW mice treated with pulse doses of cyclophosphamide
(Elsevier, 1983-11)
The immunosuppressive properties of cyclophosphamide prevent formation of anti-DNA antibodies and prolong lifespans in autoimmune NZB/NZW mice, an animal model of systemic lupus erythematosus. In the current study, NZB/NZW ...
Acquired hypogammaglobulinemia in HIV ‐positive subjects after liver transplantation
(Wiley Periodicals, Inc., 2013-12)
Introduction As more solid organ transplantations are performed in patients infected with human immunodeficiency virus ( HIV ), post‐transplant complications in this population are becoming better defined. Methods ...
Transmission of infection to liver transplant recipients from donors with infective endocarditis: lessons learned
(Wiley Periodicals, Inc., 2015-02)
Donors not meeting standard criteria, such as those with bacteremia, are now being used in response to the increasing need for organs for transplantation. Recommended strategies to prevent the occurrence of donor‐derived ...