Now showing items 31-40 of 564
Rederivation of Transgenic and Gene-Targeted Mice by Embryo Transfer
(Kluwer Academic Publishers-Plenum Publishers; Kluwer Academic Publishers ; Springer Science+Business Media, 2004-08)
Research on genetically engineered mice provides insights into the etiology, therapy, and genetic basis of human diseases. An important variable that affects the results of mouse studies is the health status of the animals. ...
Cell death in denervated skeletal muscle is distinct from classical apoptosis
(John Wiley & Sons, Inc., 2000-03-01)
Denervation of skeletal muscle is followed by the progressive loss of tissue mass and impairment of its functional properties. The purpose of the present study was to investigate the occurrence of cell death and its mechanism ...
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
(John Wiley & Sons, Ltd, 2004-04-07)
Recruiting subjects in cancer prevention and control studies
(John Wiley & Sons, Inc., 2000)
Recruitment of subjects is a critical aspect of prevention trials that is often overlooked by investigators. As a consequence, accrual time is often extended, workloads may become heavy, and resource utilization is increased ...
Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression
(Wiley Subscription Services, Inc., A Wiley Company, 2007-08)
We have previously reported that a well-characterized glycoprotein fraction containing fucose residues in an extract of Ganoderma lucidum polysaccharides (EORP) exerts certain immuno-modulation activity by stimulating ...
Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12
(Springer-Verlag, 2006-05)
Epidemiological and twin studies have consistently demonstrated a strong genetic component to prostate cancer (PCa) susceptibility. To date, numerous linkage studies have been performed to identify chromosomal regions ...
The Role of PTIP in Maintaining Embryonic Stem Cell Pluripotency
(Wiley Subscription Services, Inc., A Wiley Company, 2009-07)
Pax transactivation domain-interacting protein (PTIP) is a ubiquitously expressed, nuclear protein that is part of a histone H3K4 methyltransferase complex and is essential for embryonic development. Methylation of H3K4 ...
Estimating the power of variance component linkage analysis in large pedigrees
(Wiley Subscription Services, Inc., A Wiley Company, 2006-09)
Variance component linkage analysis is commonly used to map quantitative trait loci (QTLs) in general pedigrees. Large pedigrees are especially attractive for these studies because they provide greater power per genotyped ...
Modular cell biology: retroactivity and insulation
(John Wiley & Sons, Ltd, 2008)
Overview of Gene Targeting by Homologous Recombination
(Wiley Periodicals, Inc., 2006-10)
Formerly UNIT 9.15, this unit has been moved to the opening spot of our new chapter on Embryonic Stem Cell technology. The unit has also been updated, and now includes information about the Cre‐lox and FlP/FRT recombinase systems.