Now showing items 11-20 of 54
The gene for a novel epidermal antigen maps near the neurofibromatosis 1 gene
(Elsevier, 1992-10)
Recently the M17S1 gene, encoding an epidermal antigen thought to play a role in cell adhesion, was mapped to chromosome bands 17q11-q12, placing it in the vicinity of the gene for the genetic disorder neurofi-bromatosis ...
A microsatellite polymorphism associated with the PLC1 (phospholipase C) locus: Identification, mapping, and linkage to the MODY locus on chromosome 20
(Elsevier, 1992-07)
A highly polymorphic (dC-dA)n[middle dot](dG-dT)n dinucleotide repeat at the PLC1 locus on human chromosome 20 has been identified. Primers flanking the dinucleotide repeat were used for PCR amplification of the repeat ...
Alu-PCR: Characterization of a chromosome 6-specific hybrid mapping panel and cloning of chromosome-specific markers
(Elsevier, 1992-03)
The Alu-polymerase chain reaction (Alu-PCR) was applied to selectively amplify DNA sequences from human chromosome 6 using a single primer (A1) directed to the human Alu consensus sequence. A specific amplification pattern ...
Neural retina-specific leucine zipper gene NRL (D14S46E) maps to human chromosome 14q11.1-q11.2
(Elsevier, 1992-10)
The product of a neural retina-specific gene, NRL, belongs to the "leucine zipper" family of DNA-binding proteins and has a strong similarity to the v-maf oncogene product. The NRL gene maps to human chromosome 14 by ...
New mannose-specific lectins from garlic (Allium sativum) and ramsons (Allium ursinum) bulbs
(Elsevier, 1992-05-22)
Two new mannose-binding lectins were isolated from garlic (Allium sativum, ASA) and ramsons (Allium ursinum, AUA) bulbs, of the family Alliaceae, by affinity chromatography on immobilized mannose. The carbohydrate-binding ...
Interaction between bacteriophage [lambda] and its Escherichia coli host
(Elsevier, 1992)
Bacteriophage [lambda] relies to a large extent on processes requiring interactions between viral- and host-encoded proteins for its lytic growth, establishment of lysogeny, and release from the prophage state. Both ...
Intragenic complementation between Escherichia coli trp repressors with different defects in the tryptophan-binding pocket
(Elsevier, 1992-08-01)
Site-directed mutagenesis of the trpR gene (encoding the trp repressor, TrpR) was used to replace Gly85 with tryptophan (Trp or W), in order to place Trp near its normal location in the -tryptophan(-W)-binding pocket. The ...
Detection of oxidative mutagens in an urban air-particulate extract: a preliminary study
(Elsevier, 1992-12)
The Ames assays strains TA98 and TA100 have been useful in characterizing complex mixtures from organic solvent extracts of particles from diesel-powered vehicles, ambient air, and other sources. In this paper we report ...
Rapid generation of region-specific genomic clones by chromosome microdissection: Isolation of DNA from a region frequently deleted in malignant melanoma
(Elsevier, 1992-11)
Malignant melanoma is frequently characterized by the deletion of the long arm of chromosome 6 (usually encompassing 6q16-q21). In an effort to saturate this region with DNA markers, microdissection and molecular cloning ...