Now showing items 21-30 of 54
Introduction: A tribute to David L. Nanney, an experimental ciliatologist
(Wiley Subscription Services, Inc., A Wiley Company, 1992)
No Abstract.
Expressed sequence tags and chromosomal localization of cDNA clones from a subtracted retinal pigment epithelium library
(Elsevier, 1992-07)
Expressed sequence tags (ESTs) provide useful molecular landmarks for physical mapping and identify the position of an expressed region in the genome. The use of subtracted cDNA libraries enriched for tissue-specific genes ...
Observations consistent with autocrine stimulation of hybridoma cell growth and implications for large-scale antibody production
(Kluwer Academic Publishers; Springer Science+Business Media, 1992-04)
Existence of autocrine growth factors (aGFs) may influence the serum requirement for growth of hybridoma cells and thus significantly influence process economics. For the murine hybridoma cell line S3H5/γ2bA2, critical ...
Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I
(Elsevier, 1992-08)
The Drosophila drosulfakinin (dsk) gene encodes the cholecystokinin homologues drosulfakinin-I (DSK-I) and drosulfakinin-II (DSK-II). The naturally occurring DSKI peptide was isolated from an extract of adult flies and its ...
Estimation of the frequency of isoform–genotype discrepancies at the apolipoprotein E locus in heterozygotes for the isoforms
(Wiley Subscription Services, Inc., A Wiley Company, 1992)
Estimates of the impact of apolipoprotein E (apo E) alleles coding for the three common isoforms on plasma lipid levels assume genetic homogeneity among the genotype classes. To test this assumption, we have determined the ...
Creation of immunoglobulin diversity by intrachromosomal gene conversion
(Elsevier, 1992-12)
Not all vertebrates create an immunoglobulin repertoire through the recombination of individual members of variable (V), diversity (D) and joining (J) gene segment families. In chickens, for example, a diverse set of ...
Development and utilization of a somatic cell hybrid mapping panel to assign NotI linking probes to the long arm of human chromosome 6
(Elsevier, 1992-03)
A somatic cell hybrid mapping panel that defines seven regions of the long arm and one region of the short arm of human chromosome 6 has been developed. Utilizing this panel, 17 NotI boundary clones from a NotI linking ...
Insertional mutation of `classical' and novel genes in transgenic mice
(Elsevier, 1992-10)
Approximately 5% of established transgenic lines carry insertional mutations. The mutated genes may be directly isolated using the transgene DNA as a molecular probe. These mutants provide useful models of human inherited ...
Molecular and electrophysiological characterization of a allelic variant of the rat [alpha]6 GABAA receptor subunit
(Elsevier, 1992-11)
A 1.45 kb DNA sequence encoding the rat [alpha]6 GABAA receptor subunit (nucleotides 33-1483) was clonedfrom a Sprague-Dawley rat brain cDNA library by PCR amplification. Dideoxy sequencing of two individual clones revealed ...
A yeast artificial chromosome contig encompassing the type 1 neurofibromatosis gene
(Elsevier, 1992-07)
The yeast artificial chromosome (YAC) system (Burke et al., 1987, Science 236: 806-812) allows the direct cloning of large regions of the genome. A YAC contig map of approximately 700 kb encompassing the region surrounding ...