Now showing items 31-40 of 54
A small plasmid for recombination-based screening
(Elsevier, 1992-12-01)
We reported recently the construction of the 4.4-kb RoK-derived pMADI plasmid carrying supF [Stewart et al., Gene 106 (1991) 97-101] that does not share nt sequences with Co1E1 and therefore permits recombination-based ...
A 530kb YAC contig tightly linked to the Friedreich ataxia locus contains five CpG clusters and a new highly polymorphic microsatellite
(Springer-Verlag, 1992-07)
Friedreich ataxia (FA) is a severe autosomal recessive neurodegenerative disease. The defective gene has been previously assigned to chromosome 9q13-q21 by demonstration of tight linkage to the two independent loci D9S15 ...
Effect of calcium chloride treatment on hybridoma cell viability and growth
(Kluwer Academic Publishers; Springer Science+Business Media, 1992-10)
In order to minimize hybridoma cell damage during calcium alginate entrapment, the effect of calcium chloride treatment on hybridoma cell viability and growth was studied in terms of calcium chloride concentration and ...
Pulsatile LH secretion in women with premenstrual syndrome (PMS): Evidence for normal neuroregulation of the menstrual cycle
(Elsevier, 1992)
The premenstrual syndrome (PMS) has been proposed to result from excessive exposure to and/or withdrawal of brain opioid activity during the luteal phase. Because hypothalamic opioids are believed to modulate GnRH secretion, ...
Sequence-tagged sites (STSs) for a set of mapped markers on chromosome 21
(Elsevier, 1992-10)
Sequence tagged sites (STSs) have been proposed as a "common language" for comparing physical and genetic maps of the human genome produced by a variety of techniques. We have produced 44 STSs from 38 mapped loci on human ...
Familial transmission of alcohol use: V. Drinking patterns among spouses, Tecumseh, Michigan
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1992-01)
This study examined concordance and discordance of self-reported alcohol consumption in 184 spouse pairs drawn from a representative sample of the Tecumseh, MI community. A significant association (tau B=.57, p <.001) ...
Sequence-tagged sites (STSs) spanning 4p16.3 and the Huntington disease candidate region
(Elsevier, 1992-05)
The generation of sequence-tagged sites (STSs) has been proposed as a unifying approach to correlating the disparate results generated by genetic and various physical techniques being used to map the human genome. We have ...
Related subunits of NF-[kappa]B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2
(Elsevier, 1992-06)
The chromosomal locations of the human genes NFKB1 and NFKB2, which encode two alternative DNA binding subunits of the NF-[kappa]B complex, p105 and p49/p100, respectively, have been determined. p105 was assigned to ...
Radiation hybrid map spanning the huntington disease gene region of chromosome 4Radiation hybrid map spanning the huntington disease gene region of chromosome 4
(Elsevier, 1992-08)
Radiation hybrid (RH) mapping was used to construct a map of 11 markers in the distal 4 Mb of the short arm of chromosome 4, the region containing the Huntington disease gene. Two different methods for deriving the order ...