Now showing items 4161-4170 of 4207
Intracellular NOD-like receptors in innate immunity, infection and disease
(Blackwell Publishing Ltd, 2008-01)
The innate immune system comprises several classes of pattern-recognition receptors, including Toll-like receptors (TLRs) and nucleotide binding and oligomerization domain-like receptors (NLRs). TLRs recognize microbes on ...
HtpG, the Porphyromonas gingivalis HSP-90 homologue, induces the chemokine CXCL8 in human monocytic and microvascular vein endothelial cells
(Blackwell Publishing Ltd, 2007-06)
CXCL8 (interlukin 8, IL-8) has a diverse spectrum of biological activities including T cell, neutrophil and basophil chemotactic properties. It is produced by a wide variety of cell types and plays a significant role in ...
Determination of the physical environment within the Chlamydia trachomatis inclusion using ion-selective ratiometric probes
(Blackwell Science Ltd, 2002-05)
Chlamydia trachomatis is an obligate intracellular bacterium with a biphasic life cycle that takes place entirely within a membrane-bound vacuole termed an inclusion. The chlamydial inclusion is non-fusogenic with endosomal ...
Rebuttal to Hasty and Vijg: ‘Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity’
(Blackwell Publishing, Ltd., 2004-04)
Sorting Ourselves Out: Seeking Consensus on Trafficking in the Beta-Cell
(Munksgaard International PublishersBlackwell Publishing Ltd, 2004-01)
Polymerizing the fibre between bacteria and host cells: the biogenesis of functional amyloid fibres
(Blackwell Publishing Ltd, 2008-07)
Amyloid fibres are proteinaceous aggregates associated with several human diseases, including Alzheimer's, Huntington's and Creutzfeldt Jakob's. Disease-associated amyloid formation is the result of proteins that misfold ...
Yersinia effectors target mammalian signalling pathways
(Blackwell Science Asia Pty. Ltd., 2002-04)
Animals have an immune system to fight off challenges from both viruses and bacteria. The first line of defence is innate immunity, which is composed of cells that engulf pathogens as well as cells that release potent ...
Total Internal Reflection Fluorescence Microscopy in Cell Biology
(Munksgaard International PublishersBlackwell Publishing Ltd, 2001-11)
Weaving the neuronal net with target-derived fibroblast growth factors
(Blackwell Publishing Asia, 2009-04)
‘Accelerated aging’: a primrose path to insight?
(Blackwell Publishing, Ltd., 2004-04)
Organism envy afflicts most researchers who work on aging in mice; how frustrating it is to see the worm and fly biologists nail down milestone after milestone, citation after citation! Surely genetic trickery can produce ...