Now showing items 101-110 of 147
Identification of blood‐protein carriers of the CA 19‐9 antigen and characterization of prevalence in pancreatic diseases
(WILEY‐VCH Verlag, 2011-09)
The current best serum marker for pancreatic cancer, CA 19‐9, detects a carbohydrate antigen on multiple protein carriers. Better knowledge of the protein carriers of the CA 19‐9 antigen in various disease states may lead ...
Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2016–2018)
(Wiley Periodicals, Inc., 2019-01)
One of the most cited limitations of capillary and microchip electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments ...
Immunochemical studies on the combining site of the blood group A-special lima bean lectin
(Elsevier, 1986-08-15)
The combining site of the lima bean (Phaseolus lunatus) lectin (LBL) was studied by quantitative precipitin and precipitin-inhibition assays. The lectin precipitated best with hog gastric mucosa and human ovarian cyst blood ...
A computational approach to inferring cellular protein-binding affinities from quantitative fluorescence resonance energy transfer imaging
(WILEY-VCH Verlag, 2009-12)
Fluorescence resonance energy transfer (FRET) microscopy can measure the spatial distribution of protein interactions inside live cells. Such experiments give rise to complex data sets with many images of single cells, ...
Toward high sequence coverage of proteins in human breast cancer cells using on-line monolith-based HPLC-ESI-TOF MS compared to CE MS
(WILEY-VCH Verlag, 2006-06)
A method is developed toward high sequence coverage of proteins isolated from human breast cancer MCF10 cell lines using a 2-D liquid separations. Monolithic-capillary columns prepared by copolymerizing styrene with ...
CE of poly(amidoamine) succinamic acid dendrimers using a poly(vinyl alcohol)-coated capillary
(WILEY-VCH Verlag, 2008-01)
Various generations (G1–G8) of negatively charged poly(amidoamine) (PAMAM) succinamic acid dendrimers (PAMAM-SAH) were analyzed by CE using a poly(vinyl alcohol)-coated capillary. Due to its excellent stability and osmotic ...
Electrophoretic mobility and molecular distribution studies of poly(amidoamine) dendrimers of defined charges
(WILEY-VCH Verlag, 2006-05)
Generation 5 ethylenediamine (EDA)-cored poly(amidoamine) (PAMAM) dendrimers (E5, E denotes the EDA core and 5 the generation number) with different degrees of acetylation and carboxylation were synthesized and used as a ...
BiomarkerDigger: A versatile disease proteome database and analysis platform for the identification of plasma cancer biomarkers
(WILEY-VCH Verlag, 2009-07)
We have developed a proteome database (DB), BiomarkerDigger ( http://biomarkerdigger.org ) that automates data analysis, searching, and metadata-gathering function. The metadata-gathering function searches proteome DBs for ...
A comparative phosphoproteomic analysis of a human tumor metastasis model using a label-free quantitative approach
(WILEY-VCH Verlag, 2010-06)
Alterations in cellular phosphorylation patterns have been implicated in a number of diseases, including cancer, through multiple mechanisms. Herein we present a survey of the phosphorylation profiles of an isogenic pair ...