Now showing items 51-60 of 103
Glutamate uptake system in the presynaptic vesicle: Glutamic acid analogs as inhibitors and alternate substrates
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1993-01)
A variety of naturally occurring amino acids, their isomers, and synthetic analogs were tested for their ability to inhibit uptake of [ 3 H]glutamate into presynaptic vesicles from bovine cerebral cortex. Strongest inhibition ...
Autoradiographic quantification of muscarinic cholinergic synaptic markers in bat, shrew, and rat brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
We employed radioligand binding autoradiography to determine the distributions of pre- and postsynaptic cholinergic radioligand binding sites in the brains of two species of bat, one species of shrew, and the rat. High ...
Adverse effects associated with the short-term treatment of panic disorder with imipramine, alprazolam or placebo
(Elsevier, 1994-03)
Side effects play a significant role in the selection of drugs to be used in panic disorder/agoraphobia whose polyphobic symptomatology often includes a suspiciousness about taking drugs and a fear of undesired side effects ...
Molecular and electrophysiological characterization of a allelic variant of the rat [alpha]6 GABAA receptor subunit
(Elsevier, 1992-11)
A 1.45 kb DNA sequence encoding the rat [alpha]6 GABAA receptor subunit (nucleotides 33-1483) was clonedfrom a Sprague-Dawley rat brain cDNA library by PCR amplification. Dideoxy sequencing of two individual clones revealed ...
Tyrosine hydroxylase mRNA-containing neurons in the medial amygdaloid nucleus and the reticular nucleus of the thalamus in the Syrian hamster
(Elsevier, 1993-11)
To confirm previous immunocytochemical findings in colchicine-treated Syrian hamsters, in situ hybridization was used to investigate the distribution of TH mRNA-containing cells in the medial amygdaloid nucleus (Me) and ...
Effects of fluoxetine on weight gain and food intake in smokers who reduce nicotine intake
(Elsevier, 1991)
The effect of fluoxetine hydrochloride, a 5-HT uptake inhibitor (60 mg/day PO), in preventing weight gain associated with nicotine reduction was investigated in participants in a double-blind, placebo-controlled smoking-cessation ...
Cloning and expression of the A 2a adenosine receptor from guinea pig brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
A full-length complementary DNA (cDNA) clone encoding the guinea pig brain A 2 adenosine receptor has been isolated by polymerase chain reaction (PCR) and low-stringency-hybridization screening of a guinea pig brain cDNA ...
Effects of a selective mu opioid receptor agonist and naloxone on the intake of sodium chloride solutions
(Springer-Verlag, 1990-03)
Endogenous opioid peptides are thought to play a role in mediating the palatability or rewarding aspects of sweet tastes. There is also evidence, however, which suggests that opioids may influence the preference for the ...
Glucosylceramide in the nervous system - A mini-review
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
A reviewer of this manuscript has recommended that I warn the reader that the hypotheses offered here do not have enough experimental support to make them widely accepted.