Now showing items 241-250 of 259
Behavioral effects of dopamine agonists across the estrous cycle in rats
(Springer-Verlag, 1980-11)
The effects of apomorphine upon stereotype and bromocriptine upon wheel running and intracranial reward were examined across the estrous cycle of female rats. Apomorphine elicited stereotypy in a dose-related fashion, but ...
Use of the cortical epinephrine pressor response in rabbits as a diagnostic test for schizophrenia
(Springer-Verlag, 1963-09)
1. A careful replication of the Minz and Walaszek test failed to demonstrate its reliability as a clinical tool for diagnosing schizophrenia.
2-amino-6-trifluoromethoxy benzothiazole (PK 26124), a proposed antagonist of excitatory amino acid neurotransmission, does not produce phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
(Elsevier, 1988-07)
PK 26124, a proposed excitatory amino acid antagonist, was compared to mephenesin and phencyclldine (PCP).In pigeons, PK 26124 and mephenesin produced loss of righting that was to some extent associated with eye closure ...
Somatostatin in human pancreatic and gastric juice
(Elsevier, 1981)
Considerable amounts of IRS are secreted after secretin injection in human pancreatic juice collected during endoscopic retrograde cholangiopancreatography. The mean IRS levels in the pancreatic juice of non-diabetic ...
Regional processing of the N- and C-terminal domains of proopiomelanocortin in monkey pituitary and brain
(Elsevier, 1988-04)
The total content and extent of processing of the [gamma]3MSH and [beta]-endorphin-containing N- and C-terminal domains of proopiomelanocortin were determined in the anterior and intermediate lobes of the pituitaries and ...
Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat
(Springer-Verlag, 1993-01)
This study examined whether the anticholinergic potency of the clinically superior antipsychotic drug clozapine contributes to clozapine's anatomically-selective functional inhibition of the mesolimbic dopamine (DA) system, ...
Sensitization and tolerance to the discriminative stimulus effects of mu-opioid agonists
(Springer-Verlag, 1994-05)
The discriminative stimulus effects of several μ-opioid agonists were examined under conditions of opioid sensitization or tolerance, i.e., before and after 1-week SC infusions of naloxone or μ-opioid agonists. Rats were ...
Discriminative stimulus effects of pentobarbital in pigeons
(Springer-Verlag, 1980-11)
Pigeons were trained to discriminate the IM injection of pentobarbital (5 or 10 mg/kg) from saline in a task in which 20 consecutive pecks on one of two response keys produced access to mixed grain. Pentobarbital (1.0–17.8 ...
Experimental variables in the effects of postsession injections of strychnine sulphate on a classically conditioned response
(Springer-Verlag, 1970-01)
Postsession strychnine injections have been shown to retard acquisition rates of the classically conditioned nictitating membrane response (CCNMR) of rabbits trained at a CS-US interval of 1000 msec. The particular interval ...
Local administration of Δ9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-04)
Rationale: Cannabinoids can reduce nociceptive responses by acting on peripheral cannabinoid receptors in rodents. Objectives: The study was conducted to evaluate the hypothesis that local administration of Δ 9 ...