Now showing items 21-30 of 72
A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis
(Wiley Periodicals, Inc., 2013-11)
A single‐nucleotide polymorphism (rs2274223: A5780G:His1927Arg) in the phospholipase C epsilon gene ( PLCϵ ) was recently identified as a susceptibility locus for esophageal cancer in Chinese subjects. To determine the ...
Ototoxicity of cisplatin plus standard radiation therapy vs. accelerated radiation therapy in glioblastoma patients
(Kluwer Academic Publishers-Plenum Publishers; Springer Science + Business Media, 2005-11-05)
Purpose : To assess the effect of cisplatin (CDDP) plus concurrent radiation therapy on hearing loss. Methods : 451 patients with glioblastoma multiforme (GBM) were randomly assigned after surgery to: Arm A: Carmustine ...
Non-steroidal anti-inflammatory drug (NSAID) use and levels of a lipid oxidation marker in plasma and nipple aspirate fluids
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-05)
Non-steroidal anti-inflammatory drugs (NSAIDs) are thought to reduce cancer risk by inhibiting cyclo-oxygenases, resulting in deceased formation of inflammatory mediators and oxidative stress. We examined whether the level ...
Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-02)
Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer (LABC). The IBC phenotype is characterized by an infiltrative growth pattern, increased (lymph)angiogenesis and the propensity ...
Clinical and Radiologic Assessments to Predict Breast Cancer Pathologic Complete Response to Neoadjuvant Chemotherapy
(Kluwer Academic Publishers; Springer, 2005-08)
To prospectively compare the ability of clinical examination, mammography, vascularity-sensitive ultrasound, and magnetic resonance imaging (MRI) to determine pathologic complete response (CR) in breast cancer patients ...
RhoC-GTPase is a Novel Tissue Biomarker Associated with Biologically Aggressive Carcinomas of the Breast
(Kluwer Academic Publishers; Springer, 2005-09)
Background. There is a need for reliable predictors of breast cancer aggressiveness that will further refine the staging classification and help guide the implementation of novel therapies. We have identified RhoC as being ...
Dendriticâ cellâ based immunotherapy evokes potent antiâ tumor immune responses in CD105+ human renal cancer stem cells
(Wiley Periodicals, Inc., 2017-11)
Pharmacological Characterization of 4-hydroxy- N -desmethyl Tamoxifen, a Novel Active Metabolite of Tamoxifen
(Kluwer Academic Publishers; Springer Science+Business Media, 2004-05)
The antiestrogen tamoxifen is extensively metabolized in patients to form a series of compounds with altered affinity for estrogen receptors (ERs), the primary target of this drug. Furthermore, these metabolites exhibit a ...