Now showing items 71-72 of 72
Investigating the Role of AGO2-RAS Interaction in Mutant RAS Driven Cancers
(2022)
The RAS genes are among the most commonly mutated genes in cancer. These genes code for GTPases that act as growth factor receptor-regulated molecular switches. Mutations in RAS lead to a loss in GTP hydrolysis and cause ...
Investigating the HIV Reservoir in Hematopoietic Stem and Progenitor Cells
(2018)
Current antiretroviral therapies are not curative because they do not eradicate long-lived cells harboring HIV proviral DNA and thus, if a patient stops therapy, circulating virus will rebound. A subset of hematopoietic ...