Now showing items 21-30 of 594
Identifying and Validating Causal Genetic Alterations in Human Breast Cancer
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-04)
An important mechanism for the activation of proto-oncogenes in human breast and other cancers is gene amplification, which results in gene overexpression at both the message and the protein levels. Recent studies have ...
Induction of glutathione S -transferase-Π in Barrett's metaplasia and Barrett's adenocarcinoma cell lines
(John Wiley & Sons, Inc., 1999-02)
Barrett's metaplasia consists of columnar epithelium that replaces the normal esophageal mucosa in patients with chronic gastroesophageal reflux. Because intestinal-type Barrett's metaplasia is the major risk factor for ...
Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes
(Wiley Periodicals, Inc., 2019-02-15)
BackgroundThe authors evaluated mocetinostat (a class I/IV histone deacetylase inhibitor) in patients with urothelial carcinoma harboring inactivating mutations or deletions in CREB binding protein [CREBBP] and/or E1A ...
The role of human epidermal growth factor receptor 2 in the survival of women with estrogen and progesterone receptor-negative, invasive breast cancer: The California Cancer Registry, 1999–2004
(Wiley Subscription Services, Inc., A Wiley Company, 2008-02-15)
BACKGROUND Breast cancers that are negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) (triple negative [TN]) have been associated with high-grade histology, ...
Health status and quality of life among non-Hodgkin lymphoma survivors
(Wiley Subscription Services, Inc., A Wiley Company, 2009-07-15)
BACKGROUND: A growing body of evidence suggests that long-term survivors with 1 of the more common forms of adult cancer report a quality of life (QOL) similar to that in the general population. However, specific concerns ...
Variation in prostate cancer treatment and spending among Medicare shared savings program accountable care organizations
(Wiley Periodicals, Inc., 2018-08)
Site‐specific methylation patterns of the GAL and GALR1/2 genes in head and neck cancer: Potential utility as biomarkers for prognosis
(Wiley Periodicals, Inc.Cambridge University Press, 2017-03)
Racial/ethnic differences in clinical trial enrollment, refusal rates, ineligibility, and reasons for decline among patients at sites in the National Cancer Institute's Community Cancer Centers Program
(National Academy of SciencesWiley Periodicals, Inc., 2014-03-15)
The impact of health insurance on cancer care in disadvantaged communities
(American Cancer SocietyWiley Periodicals, Inc., 2017-04-01)