Now showing items 831-840 of 845
Economic Evidence for Decision Making in Pediatric Populations
(2022)
When a child is affected by serious or chronic illness, the illness and associated treatment process not only has significant impact on the child, but also on the child’s caregiver and other family members. Therefore, it ...
Young Families in the Community: An Exploratory Analysis of Child Welfare Contact Among Young Mothers and their Children
(2020)
The dominant frame in the literature regarding pregnancy and parenting among women with a history of child welfare contact is that of teen pregnancy as social crisis. This project reconsiders the issue of pregnancy and ...
Severe Illness Associated With Respiratory Viruses: Burden and Temporal Dynamics
(2020)
Acute lower respiratory tract infections (ALRI) are a substantial source of global morbidity and mortality, particularly among young children. Respiratory syncytial virus (RSV) and influenza are consistently observed to ...
The Molecular Underpinnings and Regulation of Amino Acid Pathways in Ewing sarcoma
(2022)
Ewing sarcoma is an aggressive pediatric bone and soft tissue tumor, most commonly driven by EWS-FLI1. The standard of care for Ewing sarcoma has not improved in decades, and by far the best predictor of poor prognosis is ...
Continuity and Change in Theory-of-Mind Development: A Neuroscientific Approach.
(2013)
This dissertation seeks a more comprehensive picture of the process of theory-of-mind development (an understanding that action is guided by internal mental states such as beliefs, desires, and intentions) by examining ...
Examination of Factors Related to Motor Performance and Physical Activity in School-aged Children with and without Down Syndrome.
(2012)
Due to widespread genetic constraints, children with Down syndrome (DS) are believed to experience deficits in several developmental domains. However, much of the research in this area is dated or inconclusive. In addition, ...
Wnt/Beta-Catenin Signaling and the Tumor Microenvironment in Ewing Sarcoma Progression
(2019)
Metastasis remains the primary cause of death in cancer patients. The invasion-metastasis cascade is dependent on crosstalk between tumor cells and the tumor microenvironment, including stromal cells, extracellular matrix, ...
Genetic Diversity, Population Structure, and Virulence Gene Polymorphisms in Nontypeable Haemophilus influenzae.
(2011)
Background: Nontypeable Haemophilus influenzae (NTHi) colonize the human pharynx asymptomatically, and are an important cause of pediatric otitis media (OM). Previous research has identified genes more prevalent among ...
Molecular Dynamics Simulation of Phase and Structural Transitions in Model Lung Surfactant Mixtures.
(2010)
Lung surfactant (LS) is a complex mixture of lipids and proteins that reduces and regulates the surface tension in the lungs, thereby decreasing the work of breathing. A thorough understanding of LS function is critical ...
Essays on Physician Incentives and Pharmaceutical Outcomes in Asthmatic Children.
(2012)
It is believed that health plans, reimbursement mechanisms and financial incentives led to health outcomes for health care utilization and medication adherence from pediatric populations. However, there is little empirical ...