Now showing items 401-410 of 416
Effects of surface morphologies on flow behavior in karst condjuits
(Proceedings of the 15th Int. Congress of Speleology, 2009)
3′‐Modified Oligonucleotides and their Conjugates
(Wiley Periodicals, Inc.Pierce Chemical Company, 2000-12)
Solid‐phase synthesis of 3′‐aminoalkyl, 3′‐thioalkyl, and 3′‐polyethyleneglycol are described. The first two are important as specific points of attachment for a large variety of reporter groups; the latter is important ...
Probing Nucleic Acid Structure with Nickel‐ and Cobalt‐Based Reagents
(Kluwer Academic PublishersWiley Periodicals, Inc., 2000-02)
The use of nickel and cobalt reagents is presented for characterizing the solvent exposure of guanine residues in DNA and RNA. These reagents promote guanine oxidation in the presence of a peracid such as monopersulfate, ...
Titelbild: Heterochromia in Designed Metallopeptides: Geometry-Selective Binding of Cd II in a De 14Novo Peptide (Angew. Chem. 35/2007)
(WILEY-VCH Verlag, 2007-09-03)
No Abstract
Empirical entropic contributions in computational docking: Evaluation in APS reductase complexes
(Wiley Subscription Services, Inc., A Wiley Company, 2008-08)
The results from reiterated docking experiments may be used to evaluate an empirical vibrational entropy of binding in ligand–protein complexes. We have tested several methods for evaluating the vibrational contribution ...
Comment on “high temperature shock tube study of the reactions CH 3 + OH → products and CH 3 OH + Ar → products”
(Wiley Subscription Services, Inc., A Wiley Company, 2009-02)
No Abstract.
Engineering Disulfide Cross‐Links in RNA Via Air Oxidation
(Oxford University PressWiley Periodicals, Inc., 2000-02)
This unit presents protocols for the synthesis of alkylthiol‐modified ribonucleosides, their incorporation into synthetic RNA, and the formation of intramolecular disulfide bonds in RNA by air oxidation. The disulfide bonds ...
Introduction to the Synthesis and Purification of Oligonucleotides
(Applied BiosystemsWiley Periodicals, Inc., 2000-02)
Modern nucleic acid synthesizers utilize phosphite triester chemistries that employ stable phosphoramidite monomers to build a growing polymer. These robust reactions allow easy generation of specific oligodeoxyribo‐ and ...
A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC)
(Kluwer Academic Publishers; Springer Science + Business Media, Inc, 2006-01-28)
Purpose: Phase II multicenter study investigated the efficacy and toxicity of the novel halogenated derivative of sulfaquixonaline Chloroquinoxaline Sulfonamide (CQS) in metastatic colorectal cancer. Experimental design: ...
Proteomic analysis of estrogen response of premalignant human breast cells using a 2-D liquid separation/mass mapping technique
(WILEY-VCH Verlag, 2006-07)
A 2-D liquid-phase separation method based on chromatofocusing and nonporous silica RP-HPLC followed by ESI-TOF-MS was used to analyze proteins in whole cell lysates from estrogen-treated and untreated premalignant, ...