Now showing items 91-100 of 2593
Entinostat is a novel therapeutic agent to treat oral squamous cell carcinoma
(Wiley Periodicals, Inc., 2020-09)
IntroductionAlterations of the epigenome may influence cancer initiation and progression. At the cellular level, histones are key regulators of chromatin accessibility and gene transcription; thus, the inhibition of histone ...
Health literacy and its association with adherence in pediatric liver transplant recipients and their parents
(OxfordWiley Periodicals, Inc., 2020-08)
ObjectiveNon- adherence to pediatric regimens is a common concern. Low health literacy is correlated with poor outcomes in adults but is understudied in pediatrics. The current project aimed to determine the relationship ...
TERT and TERT promoter in melanocytic neoplasms: Current concepts in pathogenesis, diagnosis, and prognosis
(Blackwell Publishing LtdWiley Periodicals, Inc., 2020-08)
Background and objectiveLocated on chromosome locus 5p15.33, telomerase reverse transcriptase (TERT or hTERT) encodes the catalytic subunit of telomerase which permits lengthening and preservation of telomeres following ...
PI3K/AKT/mTOR pathway activation in actinic cheilitis and lip squamous cell carcinomas
(Wiley Periodicals, Inc., 2020-09)
FAK Promotes Early Osteoprogenitor Cell Proliferation by Enhancing mTORC1 Signaling
(John Wiley & Sons, Inc., 2020-09)
Focal adhesion kinase (FAK) has important functions in bone homeostasis but its role in early osteoprogenitor cells is unknown. We show herein that mice lacking FAK in Dermo1- expressing cells exhibited low bone mass and ...
Empirical noise performance of prototype active pixel arrays employing polycrystalline silicon thin- film transistors
(Wiley Periodicals, Inc., 2020-09)
Toward a “treadmill test” for cognition: Improved prediction of general cognitive ability from the task activated brain
(John Wiley & Sons, Inc., 2020-08-15)
General cognitive ability (GCA) refers to a trait‐like ability that contributes to performance across diverse cognitive tasks. Identifying brain‐based markers of GCA has been a longstanding goal of cognitive and clinical ...
How well do doctors know their patients? Evidence from a mandatory access prescription drug monitoring program
(Stata PressWiley Periodicals, Inc., 2020-09)
Many opioid control policies target the prescribing behavior of health care providers. In this paper, we study the first comprehensive state‐level policy requiring providers to access patients’ opioid history before making ...
Weight‐Related Differences in Salience, Default Mode, and Executive Function Network Connectivity in Adolescents
(Wiley Periodicals, Inc., 2020-08)