Now showing items 81-90 of 432
The proteomes of the human eye, a highly compartmentalized organ
(National Academies PressWiley Periodicals, Inc., 2017-01)
Stepwise Solid‐Phase Synthesis of Nucleopeptides
(Wiley Periodicals, Inc.Academic Press, 2004-03)
Phosphodiester‐linked peptide‐oligonucleotide conjugates (nucleopeptides) are obtained by stepwise solid‐phase procedures. The peptide is first assembled on a suitably derivatized solid matrix and the oligonucleotide is ...
Phase II Trial of Docetaxel Chemotherapy in Patients with Incurable Adenocarcinoma of the Esophagus
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-02)
Background : Chemotherapy remains theprimary mode of treatment for metastaticcarcinoma of the esophagus. The efficacyof various chemotherapeutic regimens hasbeen studied predominantly in patients withsquamous cell carcinoma ...
Palladium‐Mediated C5 Substitution of Pyrimidine Nucleosides
(Wiley Periodicals, Inc.IRL Press, 2000-02)
One of the most efficient ways to link a reporter group to oligonucleotides is through the incorporation of a modified nucleoside during automated oligonucleotide synthesis. To be useful, it is important that the reporter ...
Unnatural Nucleosides with Unusual Base Pairing Properties
(John Wiley & Sons, 2001-07)
Synthetic modified nucleosides designed to pair in unusual ways with natural nucleobases have many potential applications in nucleic acid biochemistry. This overview lays the foundation for future protocol units on synthesis ...
Fabrication and in vitro testing of polymeric delivery system for condensed DNA
(Wiley Subscription Services, Inc., A Wiley Company, 2003-12-15)
Polyethylenimine (PEI) was combined with plasmid DNA and freeze dried following the addition of sucrose as a lyoprotectant and pore-forming agent. Freeze-dried PEI DNA condensates were dry mixed with granular polylactideglycolic ...
Chain‐Growth Polymerization of Aryl Grignards Initiated by a Stabilized NHC‐Pd Precatalyst
(WILEY‐VCH Verlag, 2012-05-14)
An N‐heterocyclic carbene‐ligated palladium catalyst was discovered to mediate living, chain‐growth polymerizations of both phenylene‐ and thiophene‐based monomers. Polymerization of a fluorene‐based monomer, on the other ...
AFM Imaging of RGD Presenting Synthetic Extracellular Matrix Using Gold Nanoparticles
(WILEY-VCH Verlag, 2008-06-11)
Several high-resolution imaging techniques such as FESEM, TEM and AFM are compared with respect to their application on alginate hydrogels, a widely used polysaccharide biomaterial. A new AFM method applicable to RGD ...