Now showing items 1-10 of 209
β-funaltrexamine antagonizes the discriminative stimulus effects of morphine but not naltrexone in pigeons
(Springer-Verlag, 1987-02)
Antagonistic actions of the irreversible, μ-selective antagonist β-funaltrexamine (β-FNA) were evaluated in pigeons trained to discriminate among intramuscular injections of morphine (5.6 mg/kg), saline, and naltrexone ...
Inhibition-mediating dopamine receptors and the control of intracranial reward
(Springer-Verlag, 1979-01)
A receptor selective agonist and antagonist of inhibition-mediating dopamine receptors (type II receptors) produced significant and dose-related alterations in bar-pressing for intracranial reward. Receptor inhibition by ...
Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-01)
Ketamine is an N -methyl- D -aspartate (NMDA) receptor antagonist with psychotogenic and dissociative effects in healthy humans. These cognitive and perceptual effects in humans are reportedly reduced by benzodiazepine ...
The effects of footshock stress on regional brain dopamine metabolism and pituitary [beta]-endorphin release in rats previously sensitized to amphetamine
(Elsevier, 1987-07)
The repeated intermittent administration of amphetamine (AMP) produces an enduring enhancement in the response of dopamine (DA) systems in the brain to a subsequent "challenge" with amphetamine. However, former amphetamine ...
The effects of chlorpromazine on psychomotor stimulant self-administration in the Rhesus monkey
(Springer-Verlag, 1972-06)
The effects of acute and chronic chlorpromazine treatment on psychomotor stimulant self-administration behavior in the Rhesus monkey were determined. Chlorpromazine treatment significantly increased the frequency of ...
Effect of photic stimulation on acetylcholine release from cat cerebral cortex
(Elsevier, 1972-01)
Cortical release of acetylcholine was assayed using the leech muscle preparation in cats with transected brainstems. Both spontaneous and elicited somatosensory and visual cortical release of acetylcholine were measured, ...
Time and dosage effects of meprobamate on visual detection
(Springer-Verlag, 1964-01)
Sixteen male subjects, 21 years and older, were run in a doubleblind own-control design under three dosages of meprobamate (400, 800 and 1600 mg) and matching placebo, to determine response curves on a visual detection ...
Selective inhibition by alcohol and cortisol of natural killer cell activity of lymphocytes from cord blood
(Elsevier, 1994-12)
1. 1. The immunosuppressive effects of drugs such as alcohol or hormones such as cortisol may be age-related. To test this hypothesis, the authors investigated the in vitro effects of ethanol (EtOH) and cortisol on Natural ...
Short-term effects of marijuana smoking on cognitive behavior in experienced male users
(Springer-Verlag, 1973-03)
The effects of smoking marijuana on the ability to use abstract concepts was tested in 12 experienced marijuana users. Each subject was tested three times, after smoking prepared 300 mg cigarettes containing either 0, 1.5 ...