Now showing items 201-209 of 209
Experimental variables in the effects of postsession injections of strychnine sulphate on a classically conditioned response
(Springer-Verlag, 1970-01)
Postsession strychnine injections have been shown to retard acquisition rates of the classically conditioned nictitating membrane response (CCNMR) of rabbits trained at a CS-US interval of 1000 msec. The particular interval ...
Local administration of Δ9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-04)
Rationale: Cannabinoids can reduce nociceptive responses by acting on peripheral cannabinoid receptors in rodents. Objectives: The study was conducted to evaluate the hypothesis that local administration of Δ 9 ...
Interaction between [3H]ethylketocyclazocine and [3H]etorphine and opioid receptors in membranes from rat brain a kinetic analysis
(Elsevier, 1986-04)
Scatchard analysis of the binding to opioid receptors of pHlethylketocyclazocine ([3H]EKC) and [3H]etorphine at equilibrium yielded biphasic plots and computer fitting of the data resulted in a minimal model of two independent ...
Stress induced facilitation of opiate catalepsy in the rat
(Elsevier, 1980)
1. 1. Adult male Sprague-Dawley rats were injected with a standard low dose of opiate (10 mg/kg of morphine sulfate).2. 2. Experimental subjects received one of two stressful procedures (tail pinch, floor cooling) while ...
Chronic use of benzodiazepines and psychomotor and cognitive test performance
(Springer-Verlag, 1986-04)
The performance of 43 long-term users (average = 5 years) of benzodiazepine (BZ) medications was examined on a battery of behavioral tasks, cognitive tests, and subjective mood rating scales. The performance of the chronic ...
Naltrexone reduces ethanol- and sucrose-reinforced responding in rhesus monkeys
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
These experiments evaluated the ability of naltrexone (NTX) to reduce selectively oral and IV ethanol-reinforced responding, and examined the ethanol-NTX interaction in terms of the competitive opioid antagonist property ...
Increased sensitivity of adenylate cyclase activity in the striatum of the rat to calmodulin and GppNHp after chronic treatment with haloperidol
(Elsevier, 1986-06)
Chronic treatment of rats with haloperidol causes behavioral supersensitivity to dopaminergic agonists and an increase in the sensitivity of adenylate cyclase activity in the striatum to stimulation by dopamine. In this ...
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-02)
Rationale : By acting on peripheral opioid receptors, opioid agonists can attenuate nociceptive responses induced by a variety of agents. Objectives : This study was conducted to characterize capsaicin-induced thermal ...