Now showing items 31-40 of 2121
Modeling intra-tumor protein expression heterogeneity in tissue microarray experiments
(John Wiley & Sons, Ltd., 2008-05-20)
Tissue microarrays (TMAs) measure tumor-specific protein expression via high-density immunohistochemical staining assays. They provide a proteomic platform for validating cancer biomarkers emerging from large-scale DNA ...
Sex Differences in Severe Pulmonary Emphysema
(2007)
Rationale: Limited data on sex differences in advanced COPD are
available.
Objectives: To compare male and female emphysema patients with
severe disease.
Methods: One thousand fifty-three patients (38.8% female) ...
The Role of Clinical Information Technology in Depression Care Management
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-01)
We examine the literature on the growing application of clinical information technology in managing depression care and highlight lessons learned from Robert Wood Johnson Foundation’s national program “Depression in Primary ...
The mental health care context and patient characteristics: Implications for provider job satisfaction
(Springer-Verlag; Association of Behavioral Healthcare Management, NCCBH, 2002-08)
This research examines job satisfaction among 282 staff providing mental health care to 574 patients with serious mental illness. The mental health staff worked in 18 Department of Veterans Affairs inpatient and outpatient ...
Artificial neural networks for prostate carcinoma risk assessment
(John Wiley & Sons, Inc., 2001-04-15)
No abstract.
Variable selection in monotone single‐index models via the adaptive LASSO
(SpringerWiley Periodicals, Inc., 2013-09-30)
We consider the problem of variable selection for monotone single‐index models. A single‐index model assumes that the expectation of the outcome is an unknown function of a linear combination of covariates. Assuming ...
Engineering Specific Cross‐Links in Nucleic Acids Using Glycol Linkers
(Wiley Periodicals, Inc., 2000-02)
One of the most convenient methods for generating oligonucleotides possessing intra‐ or interstrand cross‐links is through incorporation of oligoethylene glycol bridges by solid‐phase synthesis. The reagents are commercially ...
Antiandrogen withdrawal in castrate-refractory prostate cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2008-06-01)
BACKGROUND. Antiandrogen withdrawal is a potential therapeutic maneuver for patients with progressive prostate cancer. This study was designed to examine antiandrogen withdrawal effects within the context of a large ...
Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy
(Wiley Subscription Services, Inc., A Wiley Company, 2011-06-01)
BACKGROUND: Mitoxantrone plus prednisone and ixabepilone each have modest activity as monotherapy for second-line chemotherapy in patients with docetaxel-refractory castration-resistant prostate cancer. Clinical noncross- ...