Now showing items 191-200 of 209
Rate-dependent effect of amphetamine in rats: Extension to between-subjects effect
(Springer-Verlag, 1976-01)
Following either variable-interval or fixed-interval training, 20 rats received both 0.5 and 2.0 mg/kg of amphetamine. For both schedules, amphetamine decreased response rates of high-rate subjects and increased those of ...
A reexamination of apomorphine induced stereotypy in the rat in light of self administration experiments
(Elsevier, 1979)
1. 1. Apomorphine is known to both elicit stereotypy and to support behavioral self administration. The present report examined a possible contribution of stereotypy to self administration.2. 2. Non-contingent intraperitoneal ...
Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats
(Springer-Verlag, 1991-04)
This experiment was designed to characterize the withdrawal syndrome produced by discontinuation of treatment with escalating, non-neurotoxic doses of d -amphetamine (AMPH). AMPH withdrawal was associated with both transient ...
Response repetition in pigeons: pharmacological and behavioral specificity
(Springer-Verlag, 1986-12)
Using a reinforcement schedule that arranges random sequences of reinforcements over two response keys, low and high probabilities of repetition of non-reinforced responses were generated in two groups of pigeons ( n =3 ...
Behavioral effects of dopamine agonists across the estrous cycle in rats
(Springer-Verlag, 1980-11)
The effects of apomorphine upon stereotype and bromocriptine upon wheel running and intracranial reward were examined across the estrous cycle of female rats. Apomorphine elicited stereotypy in a dose-related fashion, but ...
Use of the cortical epinephrine pressor response in rabbits as a diagnostic test for schizophrenia
(Springer-Verlag, 1963-09)
1. A careful replication of the Minz and Walaszek test failed to demonstrate its reliability as a clinical tool for diagnosing schizophrenia.
2-amino-6-trifluoromethoxy benzothiazole (PK 26124), a proposed antagonist of excitatory amino acid neurotransmission, does not produce phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
(Elsevier, 1988-07)
PK 26124, a proposed excitatory amino acid antagonist, was compared to mephenesin and phencyclldine (PCP).In pigeons, PK 26124 and mephenesin produced loss of righting that was to some extent associated with eye closure ...
Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat
(Springer-Verlag, 1993-01)
This study examined whether the anticholinergic potency of the clinically superior antipsychotic drug clozapine contributes to clozapine's anatomically-selective functional inhibition of the mesolimbic dopamine (DA) system, ...
Sensitization and tolerance to the discriminative stimulus effects of mu-opioid agonists
(Springer-Verlag, 1994-05)
The discriminative stimulus effects of several μ-opioid agonists were examined under conditions of opioid sensitization or tolerance, i.e., before and after 1-week SC infusions of naloxone or μ-opioid agonists. Rats were ...
Discriminative stimulus effects of pentobarbital in pigeons
(Springer-Verlag, 1980-11)
Pigeons were trained to discriminate the IM injection of pentobarbital (5 or 10 mg/kg) from saline in a task in which 20 consecutive pecks on one of two response keys produced access to mixed grain. Pentobarbital (1.0–17.8 ...