Now showing items 61-70 of 209
Discriminative stimulus effects of a centrally administered, delta-opioid peptide ( d -Pen 2 - d -Pen 5 -enkephalin) in pigeons
(Springer-Verlag, 1996-10)
The present study assessed the discriminative stimulus effects of the delta-opioid agonist [ d -Pen 2 - d -Pen 5 ]enkephalin (DPDPE) in pigeons. Food-restricted pigeons were trained to discriminate between ICV injections ...
Modulation of morphine sensitization in the rat by contextual stimuli
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-08)
Rationale: The repeated administration of addictive drugs, such as amphetamine, cocaine, and morphine, produces a progressive enhancement (sensitization) of their psychomotor activating effects. We have previously shown ...
Behavioral interactions between opiate and antiepileptic drugs in the mouse
(Elsevier, 1981-04)
Morphine and related opioid compounds are known to possess proconvulsant activity based upon both electroencephalographic and behavioral criteria. The present authors previously suggested that opiate-related seizures were ...
Temperature as a dependent variable in the study of cholinergic mechanisms
(Elsevier, 1988)
Dilsaver, Steven C. and Norman F. Alessi: Temperature as a Dependent Variable in the Study of Cholinergic Mechanisms. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1988, : 1-32. 1. 1. Change in core temperature over ...
Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on κ-opioid agonists in the mouse writhing assay
(Springer-Verlag, 1994-07)
The opioid antagonist effects of systemically administered nor-binaltorphimine (nor-BNI) were evaluated against the kappa agonists CI-977, U69,593, U50,488, ethylketocyclazocine (EKC), Mr2034 and bremazocine, the mu agonist ...
Cholinergic modulation of single lateral geniculate neurons in the cat
(Elsevier, 1972-03)
The effects of physostigmine, nicotine and scopolamine were studied on the activity of single lateral geniculate neurons in the acute cat. Most of the lateral geniculate neurons selected were P-cells. These increased their ...
Behavioral sensitization: Characterization of enduring changes in rotational behavior produced by intermittent injections of amphetamine in male and female rats
(Springer-Verlag, 1984-12)
Factors influencing the behavioral sensitization (“reverse tolerance”) produced by intermittent amphetamine (AMPH) injections were studied by quantifying rotational behavior in rats that had a unilateral 6-hydroxydopamine ...
Assessing methylphenidate preference in ADHD patients using a choice procedure
(Springer-Verlag, 2004-10)
Methylphenidate (MPH) is widely used in the treatment of attention deficit hyperactivity disorder (ADHD) and is associated with positive clinical effects across a wide range of domains. Despite the clinical effectiveness ...
Effect of ethanol and of noise on reaction time in the monkey: Variation with stimulus level
(Springer-Verlag, 1980-06)
To determine whether the latency-increasing effects of ethanol were differential with respect to the intensity of the stimulus that initiated the response, three rhesus monkeys were trained on a behavioral task in which ...
Glutamate transmission and toxicity in alzheimer's disease
(Elsevier, 1988)
1. 1. Despite intensive research, the cause of Alzheimer's disease is unknown.2. 2. Glutamate is the major excitatory transmitter of the cerebral cortex and hippocampus and it appears to have an important role in learning ...