Now showing items 31-40 of 150
Strong, Safe, And Secure: Negotiating Early Fathering And Military Service Across The Deployment Cycle
(Wiley Periodicals, Inc.Brookes, 2014-09)
Military fathers of young children often endure repeated separations from their children, and these may disrupt the early parent–child relationship. Postdeployment reunification also poses challenges; disruptions that have ...
The Economics of Integrated Depression Care: The University of Michigan Study
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-01)
A goal of the Robert Wood Johnson Depression and Primary Care Initiative at the University of Michigan is to create and implement the clinical care and financial systems necessary to enable links between primary care and ...
Analyzing Binding Data
(Academic PressWiley Periodicals, Inc., 2010-07)
Measuring the rate and extent of radioligand binding provides information on the number of binding sites, and their affinity and accessibility of these binding sites for various drugs. This unit explains how to design and ...
Overview of Gene Targeting by Homologous Recombination
(Wiley Periodicals, Inc., 2007-07)
The analysis of mutant organisms and cell lines is important in determining the function of specific proteins. Recent technological advances in gene targeting by homologous recombination in mammalian systems enable the ...
Methanol exposure interferes with morphological cell movements in the Drosophila embryo and causes increased apoptosis in the CNS
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-05)
Despite the significant contributions of tissue culture and bacterial models to toxicology, whole animal models for developmental neurotoxins are limited in availability and ease of experimentation. Because Drosophila ...
Stereospecific inhibition of monoamine uptake transporters by meta-hydroxyephedrine isomers
(Springer-Verlag; Springer-Verlag Wien, 2002-10)
Meta-hydroxyephedrine (HED) comprises four stereoisomers consisting of two enantiomeric pairs related to ephedrine and pseudoephedrine. HED is transported into adrenergic neurons and radiolabeled HED has been employed in ...
NF-ΚB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity
(Wiley Subscription Services, Inc., A Wiley Company, 2005-03-01)
Cell death in outer hair cells of the mammalian inner ear induced by aminoglycoside antibiotics is mediated by reactive oxygen species (ROS) and can be prevented by antioxidants. The current study investigates the role of ...
Mixed-Methods Exploration of Group Therapy for Substance Use Disorders: Prospects for Evidence-Based Practice.
(2015)
Evidence-based treatments (EBTs) for substance use disorders (SUDs) often are not utilized in clinical practice or lag years behind in their uptake. One underappreciated dimension of this research-practice gap is a mismatch ...
Regulation of Myo-Inositol Homeostasis in Differentiated Human NT2-N Neurons
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2000-05)
We have investigated the possible role of second messengers on inositol homeostasis in NT2-N cells, human central nervous system neurons obtained by terminal differentiation of teratocarcinoma precursors. Uptake of inositol ...
A BAD link to mitochondrial cell death in the cochlea of mice with noise-induced hearing loss
(Wiley Subscription Services, Inc., A Wiley Company, 2006)
Acoustic overstimulation induces calcium overload and activation of mitochondria-mediated cell death pathways in outer hair cells (OHC) of the cochlea. However, it is not known whether these events are interrelated or ...