Now showing items 281-290 of 336
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells
(Elsevier, 1992-01)
In SK-N-SH human neuroblastoma cells, the muscarinic agonist carbachol promotes polyphosphoinositide (PPI) hydrolysis via M3 receptors and increases cyclic AMP levels through an unidentified mechanism. Activation of PPI ...
An Anti-CD2 Monoclonal Antibody That Both Inhibits and Stimulates T Cell Activation Recognizes a Subregion of CD2 Distinct from Known Ligand-Binding Sites
(Elsevier, 1993-09)
The T lymphocyte glycoprotein CD2 appears to have an important role in human T cell development and activation. A novel anti-CD2 monoclonal antibody, designated UMCD2, was shown to block E rosetting, and therefore was ...
Homogenization theory and digital imaging: A basis for studying the mechanics and design principles of bone tissue
(Wiley Subscription Services, Inc., A Wiley Company, 1994-03-25)
Bone tissue is a complex multilevel composite which has the ability to sense ad respond to its mechanical environment. It is believed that bone cells called osteocytes within the bone matrix sense the mechanical environment ...
In vivo evidence that the rise in plasma IL 6 following injection of a fever-inducing dose of LPS is mediated by IL 1[beta]
(Elsevier, 1990-05)
Although it has often been speculated that Interleukin (IL) 1[alpha] and IL 1[beta] are circulating endogenous pyrogens (EP), there are few data demonstrating an elevation of these cytokines in the plasma of febrile animals. ...
The relationship between saccharin and alcohol intake in rats
(Elsevier, 1992)
Male rats were given daily sessions during which a palatable saccharin solution was available. Based on intakes averaged over 3 days, groups with low, intermediate, or high intake of saccharin were formed. These rats were ...
Biochemical production capabilities of escherichia coli
(Wiley Subscription Services, Inc., A Wiley Company, 1993-06-05)
Microbial metabolism provides at mechanism for the conversion of substrates into useful biochemicals. Utilization of microbes in industrial processes requires a modification of their natural metabolism in order to increase ...
Purification and characterization of cytochrome P450 2E2 from hepatic microsomes of neonatal rabbits
(Elsevier, 1991-12)
The alcohol-inducible P450 2E subfamily in the rabbit has two known members that differ in only 16 amino acid residues scattered throughout the polypeptide chain. P450 2E1 has been thoroughly characterized, and is known ...
Spatial determinants of specificity in insulin action
(Kluwer Academic Publishers; Springer Science+Business Media, 1998-05)
Insulin is a potent stimulator of intermediary metabolism, however the basis for the remarkable specificity of insulin's stimulation of these pathways remains largely unknown. This review focuses on the role compartmentalization ...
Nitric oxide: Cytokine-regulation of nitric oxide in host resistance to intracellular pathogens
(Elsevier, 1994-12-01)
To discover how nitric oxide (NO) synthesis is controlled in different tissues as cells within these tissues combat intracellular pathogens, we examined three distinctively different experimental murine models designed for ...