Now showing items 51-60 of 1530
Circumstances of Witnessed Drug Overdose in New York City: Implications for Intervention
(Drug and Alcohol Dependence, 2005)
Drug users frequently witness the nonfatal and fatal drug overdoses of their peers, but often fail to intervene effectively to reduce morbidity
and mortality.We assessed the circumstances of witnessed heroin-related ...
Nutrition and Heart Failure: Impact of Drug Therapies and Management Strategies
(SAGE PublicationsWiley Periodicals, Inc., 2009-02)
Cellular Delivery of Locked Nucleic Acids (LNAs)
(Wiley Periodicals, Inc., 2002-06)
Locked nucleic acids (LNAs) are RNA derivatives that have an O‐methylene linkage between the 2 and 4 positions of the ribose. This leads to exceptionally high‐affinity binding to complementary sequences. They are synthesized ...
Challenges in Understanding Disparities in Drug Use and its Consequences
(2005)
Racial/ethnic disparities in health have long been documented in a broad
range of medical conditions in the United States. For example, Blacks have higher HIV
incidence and AIDS-related mortality than do Whites. This ...
A false-discovery-rate-based loss framework for selection of interactions
(John Wiley & Sons, Ltd., 2008-05-20)
Interaction effects have been consistently found important in explaining the variation in outcomes in many scientific research fields. Yet, in practice, variable selection including interactions is complicated due to the ...
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with ‘pleasurable buzz’ during early experimentation with smoking
(Blackwell Publishing Ltd, 2008-09)
Aims To extend the previously identified association between a single nucleotide polymorphism (SNP) in neuronal acetylcholine receptor subunit alpha-5 (CHRNA5) and nicotine dependence to current smoking and initial ...
Identification of the human CYS1 gene and candidate gene analysis in Boichis disease
(Springer-Verlag; IPNA, 2003-06)
Recessive mutations cause cystic kidney disease and a variable degree of biliary liver fibrosis in cpk mice. Recently, the responsible murine gene ( Cys1 ) was identified and expression in renal cilia demonstrated. Here ...
Adolescent inhalant use, abuse and dependence
(Blackwell Publishing Ltd, 2009-07)
Aims To compare adolescent inhalant users without DSM-IV inhalant use disorders (IUDs) to youth with IUDs (i.e. abuse or dependence) across demographic, psychosocial and clinical measures. Design Cross-sectional survey ...
Non-parametric estimation of gap time survival functions for ordered multivariate failure time data
(John Wiley & Sons, Ltd., 2004-06-30)
Times between sequentially ordered events (gap times) are often of interest in biomedical studies. For example, in a cancer study, the gap times from incidence-to-remission and remission-to-recurrence may be examined. Such ...