Now showing items 11-20 of 53
Assessing microbial competition in a hydrogen‐based membrane biofilm reactor (MBfR) using multidimensional modeling
(Cambridge University PressWiley Periodicals, Inc., 2015-09)
The membrane biofilm reactor (MBfR) is a novel technology that safely delivers hydrogen to the base of a denitrifying biofilm via gas‐supplying membranes. While hydrogen is an effective electron donor for denitrifying ...
Lack of IL‐7 and IL‐15 signaling affects interferon‐γ production by, more than survival of, small intestinal intraepithelial memory CD8 + T cells
(WILEY‐VCH Verlag, 2011-12)
Survival of antigen‐specific CD8 + T cells in peripheral lymphoid organs during viral infection is known to be dependent predominantly on IL‐7 and IL‐15. However, little is known about a possible influence of tissue ...
Localized lentivirus delivery via peptide interactions
(Wiley Periodicals, Inc.InTech, 2016-09)
Gene delivery from biomaterial scaffolds has been employed to induce the expression of tissue inductive factors for applications in regenerative medicine. The delivery of viral vectors has been described as reflecting a ...
Microbial metabolites, short‐chain fatty acids, restrain tissue bacterial load, chronic inflammation, and associated cancer in the colon of mice
(Wiley Periodicals, Inc., 2018-07)
The intestinal immune system is regulated by microbes and their metabolites. The roles of gut microbial metabolites in regulating intestinal inflammation and tumorigenesis are incompletely understood. We systematically ...
A UPLCâ MS/MS method for simultaneous determination of five flavonoids from Stellera chamaejasme L. in rat plasma and its application to a pharmacokinetic study
(Wiley Periodicals, Inc., 2018-06)
Stellera chamaejasme L. has been used as a traditional Chinese medicine for the treatment of scabies, tinea, stubborn skin ulcers, chronic tracheitis, cancer and tuberculosis. A sensitive and selective ultraâ high liquid ...
Mold‐casted non‐degradable, islet macro‐encapsulating hydrogel devices for restoration of normoglycemia in diabetic mice
(Wiley Periodicals, Inc., 2016-11)
Islet transplantation is a potential cure for diabetic patients, however this procedure is not widely adopted due to the high rate of graft failure. Islet encapsulation within hydrogels is employed to provide a three‐dimensional ...
Antitumor effector B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL‐10
(Wiley Periodicals, Inc., 2015-04)
Dynamic microRNA activity identifies therapeutic targets in trastuzumab‐resistant HER2+ breast cancer
(Wiley Periodicals, Inc.Springer, 2018-10)
MicroRNAs (miRNAs) are implicated in numerous physiologic and pathologic processes, such as the development of resistance to chemotherapy. Determining the role of miRNAs in these processes is often accomplished through ...
Recreating the perivascular niche ex vivo using a microfluidic approach
(Wiley Subscription Services, Inc., A Wiley Company, 2010-12-15)
Stem cell niches are composed of numerous microenvironmental features, including soluble and insoluble factors, cues from other cells, and the extracellular matrix (ECM), which collectively serve to maintain stem cell ...
Combinatorial lentiviral gene delivery of pro‐oligodendrogenic factors for improving myelination of regenerating axons after spinal cord injury
(Wiley Periodicals, Inc., 2019-01)
Spinal cord injury (SCI) results in paralysis below the injury and strategies are being developed that support axonal regrowth, yet recovery lags, in part, because many axons are not remyelinated. Herein, we investigated ...