Now showing items 161-169 of 169
Probing Nucleic Acid Structure with Nickel‐ and Cobalt‐Based Reagents
(Kluwer Academic PublishersWiley Periodicals, Inc., 2000-02)
The use of nickel and cobalt reagents is presented for characterizing the solvent exposure of guanine residues in DNA and RNA. These reagents promote guanine oxidation in the presence of a peracid such as monopersulfate, ...
Engineering Disulfide Cross‐Links in RNA Via Air Oxidation
(Oxford University PressWiley Periodicals, Inc., 2000-02)
This unit presents protocols for the synthesis of alkylthiol‐modified ribonucleosides, their incorporation into synthetic RNA, and the formation of intramolecular disulfide bonds in RNA by air oxidation. The disulfide bonds ...
Introduction to the Synthesis and Purification of Oligonucleotides
(Applied BiosystemsWiley Periodicals, Inc., 2000-02)
Modern nucleic acid synthesizers utilize phosphite triester chemistries that employ stable phosphoramidite monomers to build a growing polymer. These robust reactions allow easy generation of specific oligodeoxyribo‐ and ...
Local to Global Multi-Scale Multimedia Modeling of Chemical Fate and Population Exposure
(2017)
To assess environmental and human exposure to chemical emissions, two types of approaches are available: 1. intermediate- to high-resolution, substance/location-specific analyses, and 2. lower resolution, less specific ...
The Influence of Idiopathic Chronic Neck Pain on Sternocleidomastoid and Upper Trapezius Muscle Activity and Elasticity
(2022)
Approximately half of all adults will experience neck pain. Without early detection and proper treatment, neck pain will likely become chronic. Chronic neck pain is one of the primary causes of disability in the United ...
Data-Driven Environmental System Analysis: Addressing Data Gaps in Life Cycle Assessment
(2019)
Life Cycle Assessment (LCA) is a widely used analytical tool in environmental system analysis. LCA examines the environmental impacts of a product along its whole life cycle, including raw materials extraction, manufacturing, ...
Optimization and Simulation of Kidney Paired Donation Programs.
(2012)
An evolving strategy known as kidney paired donation (KPD) matches one donor-candidate pair to another pair with a complementary incompatibility,
such that the donor of the first pair donates to the candidate of the second, ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
An Alternative Outpatient Scheduling System: Improving the Outpatient Experience.
(2008)
Patient wait time has long been a recognized problem in modern outpatient health care delivery systems. Despite all the efforts to develop appointment rules and solutions, the problem of long patient waits persists. ...