Now showing items 51-60 of 336
The interaction of artemisinin with malarial hemozoin
(Elsevier, 1994-01)
[14C]Artemisinin was taken up by Plasmodium falciparum in culture and concentrated in hemozoin. In vitro, hemin and artemisinin were found to undergo a chemical reaction forming two major products which were isolated by ...
CSF somatostatin in Alzheimer's disease and major depression: Relationship to hypothalamic-pituitary-adrenal axis and clinical measures
(Elsevier, 1993)
Patients with Alzheimer's disease (AD) and major depression have been shown to have overlapping clinical symptoms and biological markers, including decreased concentrations of cerebrospinal fluid (CSF) somatostatin-like ...
Changes at multiple levels of the hypothalamo-pituitary adrenal axis following repeated electrically induced seizures
(Elsevier, 1990)
Seizures, including electrically induced seizures (ECS), activate the hypothalamo-pituitary-adrenal (HPA) axis in rats. The present studies were undertaken to characterize the effects of repeated ECS on hormone release and ...
Population balance between producing and nonproducing hybridoma clones is very sensitive to serum level, state of inoculum, and medium composition
(Wiley Subscription Services, Inc., A Wiley Company, 1992-02-05)
Secreting and nonsecreting hybridoma populations derived from the murine hybridoma cell line 167.4G5.3 were each grown in batch culture in low serum and serum-free media. Under serum-free conditions, a secreting population ...
Expression of Wild-Type and Mutant Rat Liver CTP: Phosphocholine Cytidylyltransferase in a Cytidylyltransferase-Deficient Chinese Hamster Ovary Cell Line
(Elsevier, 1994-05)
The strain 58 Chinese hamster ovary (CHO) mutant defective in CTP:phosphocholine cytidylyltransferase was characterized as an expression system for exogenous cytidylyltransferase. Strain 58 cells express less than 5% of ...
Slouching toward a systems approach to treatment
(Elsevier, 1994)
Both the health care sector generally and the alcohol and drug field are moving toward a truly systematic approach to treatment, accelerated by the anticipated advent of health care reform. There is considerable reluctance ...
Interaction of viable group a streptococci and hydrogen peroxide in killing of vascular endothelial cells
(Elsevier, 1993-05)
Previous studies have shown that the streptococcal hemolysin, streptolysin S, is capable of interacting with hydrogen peroxide (H2O2) to injure vascular endothelial cells (Free Radic. Biol. Med. 7:369-376; 1989). To extend ...
Gene expression of the insulin-like growth factors and their receptors in human neuroblastoma cell lines
(Elsevier, 1992-10)
Insulin-like growth factors (IGF) I and II are polypeptides with both growth-promoting and insulin-like metabolic effects. The developmentally specific expression of IGF I and II in the nervous system implies a role for ...