Now showing items 161-170 of 173
Cell cycle dependence of retroviral transduction: An issue of overlapping time scales
(Wiley Subscription Services, Inc., A Wiley Company, 1998-04-20)
Recombinant retroviruses are currently used as gene delivery vehicles for the purpose of gene therapy. It is generally believed that the efficiency of retroviral transduction depends on the cell cycle status of the target ...
A structured model of photosynthesis in anacystis nidulans
(Wiley Subscription Services, Inc., A Wiley Company, 1978-01)
No Abstract.
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats
(Wiley Periodicals, Inc., 2014-01)
Bacteroides thetaiotaomicron is a prominent member of the human distal gut microbiota that specializes in breaking down diet and host‐derived polysaccharides. While polysaccharide utilization has been well studied in B. ...
Mass transfer effects on microbial uptake of naphthalene from complex NAPLs
(Wiley Subscription Services, Inc., A Wiley Company, 1998-12-20)
The bioavailability of naphthalene present as a component of a complex nonaqueous phase liquid (NAPL) comprised by nine aromatic compounds was investigated. Specifically, the effects of naphthalene mass transfer from the ...
Fluid shear stress stimulates breast cancer cells to display invasive and chemoresistant phenotypes while upregulating PLAU in a 3D bioreactor
(Wiley Periodicals, Inc., 2019-11)
Breast cancer cells experience a range of shear stresses in the tumor microenvironment (TME). However most current in vitro three‐dimensional (3D) models fail to systematically probe the effects of this biophysical stimuli ...
Microporous scaffolds loaded with immunomodulatory lentivirus to study the contribution of immune cell populations to tumor cell recruitment in vivo
(Wiley Periodicals, Inc., 2020-01)
Metastases are preceded by stochastic formation of a hospitable microenvironment known as the premetastatic niche, which has been difficult to study. Herein, we employ implantable polycaprolactone scaffolds as an engineered ...
Large unit red cell cryopreservation with hydroxyethyl starch
(Elsevier, 1976-10)
Full units of red blood cells frozen with 14% hydroxyethyl starch (HES) yield cell recoveries near 97% and saline stabilities greater than 80%. Potassium leaves the cells during the freeze-thaw cycle and increases the ...
Multivariate Functional Regression and Selection
(2020)
With the pervasiveness of sensor data, real-time physiological signals and behavioral data are often collected in many biomedical studies. This thesis is motivated by data collected from a tri-axis accelerometer ActiGraph ...
Contributions to Functional Data Analysis and High-Throughput Screening Assay Analysis.
(2012)
Modern science is characterized by complex nature of available data sets. Statisticians are now developing new statistical techniques for analyzing large and complex data sets. This dissertation contributes toward analyzing ...
Using Mathematical Models to Understand Causal Mechanisms Underlying Counterintuitive Epidemiological Data
(2019)
Analyzing epidemiological data (e.g., from observational studies or surveillance) can reveal results contrary to what might be expected given a priori knowledge about the study question. In these cases, a clear mechanistic ...